Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy
The study was aimed at investigating the effects of a second?generation ACE inhibitor, lisinopril (Diroton), on central and peripheral hemodynamics in patients with dilated cardiomyopathy (DCMP). In total, 39 persons with DCMP and chronic heart failure (CHF), aged 35–55 years, were examined. Diroton...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2008-02-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1451 |
| _version_ | 1797857202498699264 |
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| author | Z. T. Astakhova T. M. Gatagonova L. M. Mosin O. T. Kotsoeva A. S. Plieva L. V. Osipova |
| author_facet | Z. T. Astakhova T. M. Gatagonova L. M. Mosin O. T. Kotsoeva A. S. Plieva L. V. Osipova |
| author_sort | Z. T. Astakhova |
| collection | DOAJ |
| description | The study was aimed at investigating the effects of a second?generation ACE inhibitor, lisinopril (Diroton), on central and peripheral hemodynamics in patients with dilated cardiomyopathy (DCMP). In total, 39 persons with DCMP and chronic heart failure (CHF), aged 35–55 years, were examined. Diroton dose was titrated from low (2,5 mg/d) to high (10 mg/d). The treatment lasted for 12 months. Longterm Diroton therapy, as a part of complex pharmaceutical treatment, was associated with significant improvement in total and regional hemodynamics in DCMP patients: left ventricular ejection fraction increased, dilated myocardium volumes and sizes reduced, together with reduction in temporal rheography parameters and increase in velocity ones. Diroton therapy also improved clinical course of CHF and circadian blood pressure profile. |
| first_indexed | 2024-04-09T20:52:53Z |
| format | Article |
| id | doaj.art-27cc8d7d258540c899cbe5f6735de1dd |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:52:53Z |
| publishDate | 2008-02-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-27cc8d7d258540c899cbe5f6735de1dd2023-03-29T21:23:15Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202008-02-010132351239Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathyZ. T. Astakhova0T. M. Gatagonova1L. M. Mosin2O. T. Kotsoeva3A. S. Plieva4L. V. Osipova5Северо-Осетинская медицинская академияСеверо-Осетинская медицинская академияСеверо-Осетинская медицинская академияСеверо-Осетинская медицинская академияСеверо-Осетинская медицинская академияСеверо-Осетинская медицинская академияThe study was aimed at investigating the effects of a second?generation ACE inhibitor, lisinopril (Diroton), on central and peripheral hemodynamics in patients with dilated cardiomyopathy (DCMP). In total, 39 persons with DCMP and chronic heart failure (CHF), aged 35–55 years, were examined. Diroton dose was titrated from low (2,5 mg/d) to high (10 mg/d). The treatment lasted for 12 months. Longterm Diroton therapy, as a part of complex pharmaceutical treatment, was associated with significant improvement in total and regional hemodynamics in DCMP patients: left ventricular ejection fraction increased, dilated myocardium volumes and sizes reduced, together with reduction in temporal rheography parameters and increase in velocity ones. Diroton therapy also improved clinical course of CHF and circadian blood pressure profile.https://russjcardiol.elpub.ru/jour/article/view/1451dilated cardiomyopathychronic heart failurelongjterm treatmentdirotoncentral and peripheral hemodynamicsrheography |
| spellingShingle | Z. T. Astakhova T. M. Gatagonova L. M. Mosin O. T. Kotsoeva A. S. Plieva L. V. Osipova Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy Российский кардиологический журнал dilated cardiomyopathy chronic heart failure longjterm treatment diroton central and peripheral hemodynamics rheography |
| title | Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy |
| title_full | Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy |
| title_fullStr | Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy |
| title_full_unstemmed | Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy |
| title_short | Effects of longJterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy |
| title_sort | effects of longjterm lisinopril therapy on central and peripheral hemodynamics in patients with dilated cardiomyopathy |
| topic | dilated cardiomyopathy chronic heart failure longjterm treatment diroton central and peripheral hemodynamics rheography |
| url | https://russjcardiol.elpub.ru/jour/article/view/1451 |
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