In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser Systems

Purpose: to compare in vivo histomorphologic structure of cornea after the FemtoLASIK procedure using femtolaser systems Femto Visum (Russia) and Femto LDV Z6 (Switzerland). Patients and methods: The study was carried for 70 eyes from 70 patients with low to moderate myopia after FemtoLASIK procedur...

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Main Authors: A. V. Doga, I. A. Mushkova, A. N. Karimova, E. V. Kechin
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2018-10-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/686
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author A. V. Doga
I. A. Mushkova
A. N. Karimova
E. V. Kechin
author_facet A. V. Doga
I. A. Mushkova
A. N. Karimova
E. V. Kechin
author_sort A. V. Doga
collection DOAJ
description Purpose: to compare in vivo histomorphologic structure of cornea after the FemtoLASIK procedure using femtolaser systems Femto Visum (Russia) and Femto LDV Z6 (Switzerland). Patients and methods: The study was carried for 70 eyes from 70 patients with low to moderate myopia after FemtoLASIK procedure. Group 1 (Femto Visum) included 36 eyes (n = 36) there the flap were formed using femtolaser Femto Visum («Optosystems», Russia), group 2 (Femto LDV Z6) included 34 eyes (n = 34) and Femto LDV Z6 was used («Ziemer Ophthalmic Systems AG», Switzerland). The excimer laser ablation was performed with Microscan Visum system («Optosystems», Russia) in both groups. The Femto Visum and Femto LDV Z6 groups were comparable in terms of pre-operative data (age, sex, corneal curvature, central corneal thickness, sphere, cylinder, spherical equivalent) (p > 0.05). In vivo histomorphological structure of the cornea was examined using confocal microscope Confoscan 4 (Nidek, Japan) 1 week, 1, 3, 6, and 12 months after FemtoLASIK. The endothelial cell density (ECD) was measured with endothelial microscope (EM-3000, Tomey, Japan) before surgery and 12 months after FemtoLASIK. Results: The main in vivo histomorphological cornea changes occurred in the anterior and middle layers of the corneal stroma during post-operative period in both groups (Femto Visum and Femto LDV Z6). The underlying corneal structures remained intact. There was no statistically significant difference between the two groups (p > 0.05). Twelve months postoperatively, the loss of ECD was 0.31 % in the Femto Visum group and 0.33 % in the Femto LDV Z6 group (p > 0,05). Conclusions: FemtoLASIK procedures using Femto Visum (Russia) and Femto LDV Z6 (Switzerland) lead to similar histomorphological cornea changes in post-operative period (p > 0.05) and they are safe for corneal structure in the treatment of myopia.
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spelling doaj.art-27cca1a9955f475bb959a23cfb65ee2b2023-03-13T09:08:38ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452018-10-0115326427210.18008/1816-5095-2018-3-264-272451In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser SystemsA. V. Doga0I. A. Mushkova1A. N. Karimova2E. V. Kechin3ФГАУ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения Российской ФедерацииФГАУ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения Российской ФедерацииФГАУ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения Российской ФедерацииФГАУ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения Российской ФедерацииPurpose: to compare in vivo histomorphologic structure of cornea after the FemtoLASIK procedure using femtolaser systems Femto Visum (Russia) and Femto LDV Z6 (Switzerland). Patients and methods: The study was carried for 70 eyes from 70 patients with low to moderate myopia after FemtoLASIK procedure. Group 1 (Femto Visum) included 36 eyes (n = 36) there the flap were formed using femtolaser Femto Visum («Optosystems», Russia), group 2 (Femto LDV Z6) included 34 eyes (n = 34) and Femto LDV Z6 was used («Ziemer Ophthalmic Systems AG», Switzerland). The excimer laser ablation was performed with Microscan Visum system («Optosystems», Russia) in both groups. The Femto Visum and Femto LDV Z6 groups were comparable in terms of pre-operative data (age, sex, corneal curvature, central corneal thickness, sphere, cylinder, spherical equivalent) (p > 0.05). In vivo histomorphological structure of the cornea was examined using confocal microscope Confoscan 4 (Nidek, Japan) 1 week, 1, 3, 6, and 12 months after FemtoLASIK. The endothelial cell density (ECD) was measured with endothelial microscope (EM-3000, Tomey, Japan) before surgery and 12 months after FemtoLASIK. Results: The main in vivo histomorphological cornea changes occurred in the anterior and middle layers of the corneal stroma during post-operative period in both groups (Femto Visum and Femto LDV Z6). The underlying corneal structures remained intact. There was no statistically significant difference between the two groups (p > 0.05). Twelve months postoperatively, the loss of ECD was 0.31 % in the Femto Visum group and 0.33 % in the Femto LDV Z6 group (p > 0,05). Conclusions: FemtoLASIK procedures using Femto Visum (Russia) and Femto LDV Z6 (Switzerland) lead to similar histomorphological cornea changes in post-operative period (p > 0.05) and they are safe for corneal structure in the treatment of myopia.https://www.ophthalmojournal.com/opht/article/view/686фемтолазикфемтосекундный лазерфемто визумfemto ldv z6роговичный клапанроговицаконфокальная микроскопия
spellingShingle A. V. Doga
I. A. Mushkova
A. N. Karimova
E. V. Kechin
In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser Systems
Oftalʹmologiâ
фемтолазик
фемтосекундный лазер
фемто визум
femto ldv z6
роговичный клапан
роговица
конфокальная микроскопия
title In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser Systems
title_full In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser Systems
title_fullStr In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser Systems
title_full_unstemmed In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser Systems
title_short In Vivo Histomorphologic Structure of Cornea after FemtoLASIK Using Various Femtosecond Laser Systems
title_sort in vivo histomorphologic structure of cornea after femtolasik using various femtosecond laser systems
topic фемтолазик
фемтосекундный лазер
фемто визум
femto ldv z6
роговичный клапан
роговица
конфокальная микроскопия
url https://www.ophthalmojournal.com/opht/article/view/686
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AT iamushkova invivohistomorphologicstructureofcorneaafterfemtolasikusingvariousfemtosecondlasersystems
AT ankarimova invivohistomorphologicstructureofcorneaafterfemtolasikusingvariousfemtosecondlasersystems
AT evkechin invivohistomorphologicstructureofcorneaafterfemtolasikusingvariousfemtosecondlasersystems