Resistance Mechanisms of the Metastatic Tumor Microenvironment to Anti-Angiogenic Therapy

Angiogenesis describes the formation of blood vessels from an existing vascular network. Anti-angiogenic drugs that target tumor blood vessels have become standard of care in many cancer entities. Though very promising results in preclinical evaluation, anti-angiogenic treatments fell short of expec...

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Bibliographic Details
Main Authors: Lars M. Schiffmann, Christiane J. Bruns, Thomas Schmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.897927/full