Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study

Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study

Disruptions in oxidative metabolism may occur in multiple sclerosis and other demyelinating neurological diseases. The impact of demyelination on metabolic rate is also not understood. It is possible that mitochondrial damage may be associated with many such neurological disorders. To study oxidativ...

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Bibliographic Details
Main Authors:	Mada Hashem, Qandeel Shafqat, Ying Wu, Jong M. Rho, Jeff F. Dunn
Format:	Article
Language:	English
Published:	Elsevier 2022-04-01
Series:	NeuroImage
Subjects:	Cuprizone mouse model Demyelination Cerebral metabolic rate of oxygen Cytochrome C oxidase NIRS MRI
Online Access:	http://www.sciencedirect.com/science/article/pii/S1053811922000647

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