Molecular modeling, dynamics simulation and characterization of human inositol hexakisphosphate kinase 1 (IP6K1) related to diabetes

Inositol hexakisphosphate kinase-1 (IP6K1) protein plays an important role in insulin signaling producing IP7 that inhibit the action of protein kinase B (Akt). Inhibition of IP6K1 has been proposed as a novel way to enhance insulin signaling. Characterization and binding interaction of IP6K1 is es...

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Bibliographic Details
Main Authors: O.O. Elekofehinti, Y.V. Aladenika, Y.R. Alli-Smith, O.C. Ejelonu, A.O. Lawal
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2019-04-01
Series:Journal of Applied Sciences and Environmental Management
Subjects:
Online Access:https://www.ajol.info/index.php/jasem/article/view/185428