Cordycepin Suppresses Endothelial Cell Proliferation, Migration, Angiogenesis, and Tumor Growth by Regulating Focal Adhesion Kinase and p53

Cordycepin Suppresses Endothelial Cell Proliferation, Migration, Angiogenesis, and Tumor Growth by Regulating Focal Adhesion Kinase and p53

Focal adhesion kinase (FAK) plays an important role in vascular development, including the regulation of endothelial cell (EC) adhesion, migration, proliferation, and survival. 3’-deoxyadenosine (cordycepin) is known to suppress FAK expression, cell migration, and the epithelial⁻...

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Bibliographic Details
Main Authors: Yi-Ting Lin, Shu-Man Liang, Ya-Ju Wu, Yi-Ju Wu, Yi-Jhu Lu, Yee-Jee Jan, Bor-Sheng Ko, Yung-Jen Chuang, Song-Kun Shyue, Cheng-Chin Kuo, Jun-Yang Liou
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
angiogenesis
cordycepin
endothelial cells
FAK
p53
Online Access:https://www.mdpi.com/2072-6694/11/2/168

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