Serrated Colorectal Lesions: An Up-to-Date Review from Histological Pattern to Molecular Pathogenesis

Serrated Colorectal Lesions: An Up-to-Date Review from Histological Pattern to Molecular Pathogenesis

Until 2010, colorectal serrated lesions were generally considered as harmless lesions and reported as hyperplastic polyps (HPs) by pathologists and gastroenterologists. However, recent evidence showed that they may bear the potential to develop into colorectal carcinoma (CRC). Therefore, the World H...

Full description

Bibliographic Details
Main Authors:	Martino Mezzapesa, Giuseppe Losurdo, Francesca Celiberto, Salvatore Rizzi, Antonio d’Amati, Domenico Piscitelli, Enzo Ierardi, Alfredo Di Leo
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	International Journal of Molecular Sciences
Subjects:	colorectal cancer colorectal serrated lesions sessile serrated lesions serrated pathway microsatellite instability CpG island methylator phenotype
Online Access:	https://www.mdpi.com/1422-0067/23/8/4461

Similar Items

Aberrant PRDM2 methylation as an early event in serrated lesions destined to evolve into microsatellite‐instable colorectal cancers
by: David EFWM vanToledo, et al.
Published: (2024-03-01)

The relationship between serum lipid levels and colorectal serrated lesions: A systematic review and meta-analysis
by: Xuerui Wang, et al.
Published: (2022-10-01)

The clinical impact of serrated colorectal polyps
by: O'Connell BM, et al.
Published: (2017-02-01)

Hyperplastic polyp or sessile serrated lesion? The contribution of serial sections to reclassification
by: Diana R. Jaravaza, et al.
Published: (2020-12-01)

An “expressionistic” look at serrated precancerous colorectal lesions
by: Giancarlo Marra
Published: (2021-01-01)

Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas
by: Hironori Aoki, et al.
Published: (2024-03-01)

Endoscopic Features of Mucous Cap Polyps: A Way to Predict Serrated Polyps
by: Brian T. Moy, et al.
Published: (2018-07-01)

The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer
by: Fatima Domenica Elisa De Palma, et al.
Published: (2019-07-01)

Characteristics and outcomes of endoscopically resected colorectal cancers that arose from sessile serrated adenomas and traditional serrated adenomas
by: Ji Yeon Seo, et al.
Published: (2016-07-01)

Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma
by: Sung Jae Park, et al.
Published: (2018-01-01)

The histologic features, molecular features, detection and management of serrated polyps: a review
by: Jin-Dong Wang, et al.
Published: (2024-03-01)

Clinical Features and Predictors of Dysplasia in Proximal Sessile Serrated Lesions
by: Yi Yuan Tan, et al.
Published: (2021-07-01)

TXI (Texture and Color Enhancement Imaging) for Serrated Colorectal Lesions
by: Toshihiro Nishizawa, et al.
Published: (2021-12-01)

Frequency of serrated polyposis syndrome recognition by community endoscopists
by: Connor D. McWhinney, et al.
Published: (2023-09-01)

Clinicopathologic and endoscopic features of sessile serrated lesions and conventional adenomas: a large inpatient population-based study in China
by: Chang Tan, et al.
Published: (2024-04-01)

Global Methylome Scores Correlate with Histological Subtypes of Colorectal Carcinoma and Show Different Associations with Common Clinical and Molecular Features
by: María del Carmen Turpín-Sevilla, et al.
Published: (2021-10-01)

Serrated polyposis syndrome with multiple inverted lesions in the colon: Case report and elucidation of morphogenetic mechanism
by: Chihiro Yoshikawa, et al.
Published: (2022-04-01)

Clinical and endoscopic characteristics of sessile serrated lesions with dysplasia/carcinoma
by: Peel Jung, et al.
Published: (2023-05-01)

Validation of hypermethylated DNA regions found in colorectal cancers as potential aging-independent biomarkers of precancerous colorectal lesions
by: Sija Sajibu, et al.
Published: (2023-10-01)

Clinical characteristics of patients with serrated polyposis syndrome in Korea: comparison with Western patients
by: Eun Ran Kim, et al.
Published: (2017-07-01)

Two histologically colorectal carcinomas subsets from the serrated pathway show different methylome signatures and diagnostic biomarkers
by: José García-Solano, et al.
Published: (2018-11-01)

MLH1–93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutation
by: Lochlan J. Fennell, et al.
Published: (2018-01-01)

Evolving pathologic concepts of serrated lesions of the colorectum
by: Jung Ho Kim, et al.
Published: (2020-07-01)

Long-Term Incidence of Advanced Colorectal Neoplasia in Patients with Serrated Polyposis Syndrome: Experience in a Single Academic Centre
by: Daniel Rodríguez-Alcalde, et al.
Published: (2021-03-01)

Research Progress on the Correlation of Dyslipidemia with Colorectal Serrated Lesions and Colorectal Cancer
by: RAN Dongsheng, LU Yanyan, XIN Chunling, MA Yingcai
Published: (2024-04-01)

Colorectal Adenocarcinoma with an Alternative Serrated Pathway
by: Makoto Eizuka, et al.
Published: (2018-04-01)

Left-Sided Diverticulosis is a Risk Factor for Distal Colon Polyps
by: Shashank Sarvepalli, et al.
Published: (2020-03-01)

Significance of Micromorphological Characteristics and Expression of Intermediate Filament Proteins CK7 and CK20 in the Differential Diagnosis of Serrated Lesions of the Colorectum
by: Ivan Ilić, et al.
Published: (2023-02-01)

Narrow Band Imaging versus White Light for the Detection of Sessile Serrated Colorectal Lesions: A Randomized Clinical Trial
by: Alexandre Oliveira Ferreira, et al.
Published: (2022-10-01)

Risk Factors in Serrated Pathway Lesions: N-Glycosylation Profile as a Potential Biomarker of Progression to Malignancy
by: Henrique Fernandes-Mendes, et al.
Published: (2024-01-01)

Narrow band imaging versus white light for detecting sessile serrated lesion: A prospective randomized multicenter study
by: Dominic Staudenmann, et al.
Published: (2022-04-01)

Telomere length differences between colorectal polyp subtypes: a colonoscopy-based case-control study
by: Sheetal Hardikar, et al.
Published: (2018-05-01)

Clinicopathological Correlates of Dysplastic Sessile Serrated Lesion: A Prospective Cohort Study With a High Detection Rate
by: Mehul Lamba, et al.
Published: (2022-01-01)

A clinical-morphological study of colorectal polyps with emphasis on serrated lesions
by: Avnika Jasuja, et al.
Published: (2024-01-01)

Serrated Polyposis Syndrome: A Literature Review
by: Guilherme Campos Stephanini, et al.
Published: (2023-12-01)

Transcriptome of sessile serrated adenoma/polyps is associated with MSI‐high colorectal cancer and decreased expression of CDX2
by: Daisuke Ohki, et al.
Published: (2022-12-01)

Pure somatic pathogenic variation profiles for patients with serrated polyposis syndrome: a case series
by: Misaki Hidaka, et al.
Published: (2022-11-01)

Different TERT Expression between Colorectal Adenoma and Serrated Polyp
by: Soo-Jung Jung, et al.
Published: (2020-09-01)

Serrated neoplasia pathway as an alternative route of colorectal cancer carcinogenesis
by: Soon Young Kim, et al.
Published: (2018-07-01)

Disentangling tumorigenesis-associated DNA methylation changes in colorectal tissues from those associated with ageing
by: Stephany Orjuela, et al.
Published: (2022-06-01)