Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk
Background and Aim: Antimicrobial resistance poses a major threat to global public health. Foodstuff of animal origin can serve as potential vehicles for the dissemination of antimicrobial-resistant bacteria and resistance genes to consumers. In view of the lack of knowledge about antimicrobial resi...
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| Format: | Article |
| Language: | English |
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Veterinary World
2021-05-01
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| Series: | Veterinary World |
| Subjects: | |
| Online Access: | http://www.veterinaryworld.org/Vol.14/May-2021/3.pdf |
| _version_ | 1830302201151488000 |
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| author | Abimael E. Silva Júnior Priscylla C. Vasconcelos Mauro M. S. Saraiva Lauro Santos Filho Núbia M. V. Silva Patricia E. N. Givisiez Celso J. B. Oliveira |
| author_facet | Abimael E. Silva Júnior Priscylla C. Vasconcelos Mauro M. S. Saraiva Lauro Santos Filho Núbia M. V. Silva Patricia E. N. Givisiez Celso J. B. Oliveira |
| author_sort | Abimael E. Silva Júnior |
| collection | DOAJ |
| description | Background and Aim: Antimicrobial resistance poses a major threat to global public health. Foodstuff of animal origin can serve as potential vehicles for the dissemination of antimicrobial-resistant bacteria and resistance genes to consumers. In view of the lack of knowledge about antimicrobial resistance in bacteria associated with goat milk, the aim of this study was to report species-level identification and antimicrobial susceptibility profiles of a large collection of Staphylococcus spp. isolates recovered from raw goat milk in Brazil.
Materials and Methods: A total of 434 Staphylococcus spp. isolates originated from 510 goat milk samples in Northeast Brazil were investigated. The isolates were obtained by conventional microbiological methods. Species identification and antimicrobial susceptibility testing were performed by means of a semi-automated system using a panel for biochemical tests and broth microdilution method for 19 antimicrobial drugs.
Results: Although Staphylococcus aureus (22.6%) accounted for the majority of the isolates, a total of 13 different non-aureus staphylococci spp. were identified. High resistance rates against erythromycin (40.8%), and the beta-lactams ampicillin (45.9%) and penicillin (42.9%) were observed among S. aureus isolates. The most significant findings were related to the resistance against quinupristin-dalfopristin, a drug of last resort used in human medicine to treat infections caused by vancomycin-resistant S. aureus and enterococci.
Conclusion: The high diversity of Staphylococcus spp. showing phenotypic resistance against different antimicrobial drugs encourages further investigations on the real impact of these bacteria as reservoirs of antimicrobial resistance genes to consumers. Furthermore, the potential impact of technological processes, such as pasteurization, fermentation, and maturation, on the maintenance and dissemination of antimicrobial resistance among the microbial populations in milk and dairy products must also be investigated. |
| first_indexed | 2024-12-19T09:02:53Z |
| format | Article |
| id | doaj.art-27deb438c9ee48b286f819f72172142b |
| institution | Directory Open Access Journal |
| issn | 0972-8988 2231-0916 |
| language | English |
| last_indexed | 2024-12-19T09:02:53Z |
| publishDate | 2021-05-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | Veterinary World |
| spelling | doaj.art-27deb438c9ee48b286f819f72172142b2022-12-21T20:28:25ZengVeterinary WorldVeterinary World0972-89882231-09162021-05-011451074107910.14202/vetworld.2021.1074-1079Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milkAbimael E. Silva Júnior0https://orcid.org/0000-0002-7563-5954Priscylla C. Vasconcelos1https://orcid.org/0000-0002-7578-4087Mauro M. S. Saraiva2https://orcid.org/0000-0003-1875-4495Lauro Santos Filho3https://orcid.org/0000-0002-2202-1094Núbia M. V. Silva4https://orcid.org/0000-0002-9800-9585Patricia E. N. Givisiez5https://orcid.org/0000-0002-2480-1780Celso J. B. Oliveira6https://orcid.org/0000-0002-7761-0697Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba, Brazil.Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba, Brazil.Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba, Brazil.Department of Pharmaceutical Sciences, College of Health Sciences, Federal University of Paraiba, Brazil.Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba, Brazil.Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba, Brazil.Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba, Brazil.Background and Aim: Antimicrobial resistance poses a major threat to global public health. Foodstuff of animal origin can serve as potential vehicles for the dissemination of antimicrobial-resistant bacteria and resistance genes to consumers. In view of the lack of knowledge about antimicrobial resistance in bacteria associated with goat milk, the aim of this study was to report species-level identification and antimicrobial susceptibility profiles of a large collection of Staphylococcus spp. isolates recovered from raw goat milk in Brazil. Materials and Methods: A total of 434 Staphylococcus spp. isolates originated from 510 goat milk samples in Northeast Brazil were investigated. The isolates were obtained by conventional microbiological methods. Species identification and antimicrobial susceptibility testing were performed by means of a semi-automated system using a panel for biochemical tests and broth microdilution method for 19 antimicrobial drugs. Results: Although Staphylococcus aureus (22.6%) accounted for the majority of the isolates, a total of 13 different non-aureus staphylococci spp. were identified. High resistance rates against erythromycin (40.8%), and the beta-lactams ampicillin (45.9%) and penicillin (42.9%) were observed among S. aureus isolates. The most significant findings were related to the resistance against quinupristin-dalfopristin, a drug of last resort used in human medicine to treat infections caused by vancomycin-resistant S. aureus and enterococci. Conclusion: The high diversity of Staphylococcus spp. showing phenotypic resistance against different antimicrobial drugs encourages further investigations on the real impact of these bacteria as reservoirs of antimicrobial resistance genes to consumers. Furthermore, the potential impact of technological processes, such as pasteurization, fermentation, and maturation, on the maintenance and dissemination of antimicrobial resistance among the microbial populations in milk and dairy products must also be investigated.http://www.veterinaryworld.org/Vol.14/May-2021/3.pdfantimicrobial resistancedairy goatsfood safetystaphylococcus |
| spellingShingle | Abimael E. Silva Júnior Priscylla C. Vasconcelos Mauro M. S. Saraiva Lauro Santos Filho Núbia M. V. Silva Patricia E. N. Givisiez Celso J. B. Oliveira Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk Veterinary World antimicrobial resistance dairy goats food safety staphylococcus |
| title | Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk |
| title_full | Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk |
| title_fullStr | Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk |
| title_full_unstemmed | Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk |
| title_short | Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk |
| title_sort | antimicrobial susceptibility profiles of staphylococcus spp contaminating raw goat milk |
| topic | antimicrobial resistance dairy goats food safety staphylococcus |
| url | http://www.veterinaryworld.org/Vol.14/May-2021/3.pdf |
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