Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex.

The B7 family represents one of the best-studied subgroups within the Ig superfamily, yet new interactions continue to be discovered. However, this binding promiscuity represents a major challenge for defining the biological contribution of each specific interaction. We developed a strategy for addr...

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Bibliographic Details
Main Authors: Sarah C Garrett-Thomson, Aldo Massimi, Elena V Fedorov, Jeffrey B Bonanno, Lisa Scandiuzzi, Brandan Hillerich, Ronald D Seidel, James D Love, Scott J Garforth, Chandan Guha, Steven C Almo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233578