Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice
Apical periodontitis is an immune inflammatory response around periapical tissues as a result of pathogens invasion into the root canal. The host immunoinflammatory response could determine the progression of this disease, which involves the recruitment of immune cells, and the release of several cy...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-02-01
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| Series: | Data in Brief |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340921010611 |
| _version_ | 1819279105121583104 |
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| author | Thaise Mayumi Taira Vítor Luís Ribeiro Yuri Jivago Silva Ribeiro Raquel Assed Bezerra da Silva Léa Assed Bezerra da Silva Marília Pacífico Lucisano Politi Lúcia Helena Faccioli Francisco Wanderley Garcia Paula-Silva |
| author_facet | Thaise Mayumi Taira Vítor Luís Ribeiro Yuri Jivago Silva Ribeiro Raquel Assed Bezerra da Silva Léa Assed Bezerra da Silva Marília Pacífico Lucisano Politi Lúcia Helena Faccioli Francisco Wanderley Garcia Paula-Silva |
| author_sort | Thaise Mayumi Taira |
| collection | DOAJ |
| description | Apical periodontitis is an immune inflammatory response around periapical tissues as a result of pathogens invasion into the root canal. The host immunoinflammatory response could determine the progression of this disease, which involves the recruitment of immune cells, and the release of several cytokines in the lesion site. The 5-lipoxygenase pathway has been activated in some osteolytic diseases due to its capacity to interfere in the proliferation and differentiation of bone cells, including the osteoclasts. As mean to understand the inflammatory genes regulation in the apical periodontitis progression, we evaluated the network of 66 genes related to cytokines, chemokines and other inflammatory mediators and receptors in the wild-type (WT) and 5-lipoxygenase enzyme genetically deficient mice (KO). This article presents data not published but related to the research article “Effects of 5-lipoxygenase gene disruption on inflammation, osteoclastogenesis and bone resorption in polymicrobial apical periodontitis” . |
| first_indexed | 2024-12-24T00:22:36Z |
| format | Article |
| id | doaj.art-27e608b27df64a449b9991f9d93cd357 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-24T00:22:36Z |
| publishDate | 2022-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-27e608b27df64a449b9991f9d93cd3572022-12-21T17:24:32ZengElsevierData in Brief2352-34092022-02-0140107787Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout miceThaise Mayumi Taira0Vítor Luís Ribeiro1Yuri Jivago Silva Ribeiro2Raquel Assed Bezerra da Silva3Léa Assed Bezerra da Silva4Marília Pacífico Lucisano Politi5Lúcia Helena Faccioli6Francisco Wanderley Garcia Paula-Silva7Department of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, BrazilDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, BrazilDepartment of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, BrazilDepartment of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, BrazilDepartment of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, BrazilDepartment of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, BrazilDepartamento de Análises Clínicas, Toxicológicas e Bromatológicas da Faculdade de Ciências Farmacêuticas de Ribeirão Preto da Universidade de São Paulo, Ribeirão Preto, São Paulo, BrazilDepartment of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, Brazil; Corresponding author.Apical periodontitis is an immune inflammatory response around periapical tissues as a result of pathogens invasion into the root canal. The host immunoinflammatory response could determine the progression of this disease, which involves the recruitment of immune cells, and the release of several cytokines in the lesion site. The 5-lipoxygenase pathway has been activated in some osteolytic diseases due to its capacity to interfere in the proliferation and differentiation of bone cells, including the osteoclasts. As mean to understand the inflammatory genes regulation in the apical periodontitis progression, we evaluated the network of 66 genes related to cytokines, chemokines and other inflammatory mediators and receptors in the wild-type (WT) and 5-lipoxygenase enzyme genetically deficient mice (KO). This article presents data not published but related to the research article “Effects of 5-lipoxygenase gene disruption on inflammation, osteoclastogenesis and bone resorption in polymicrobial apical periodontitis” .http://www.sciencedirect.com/science/article/pii/S2352340921010611Arachidonic acidLeukotrienesInflammationBone resorption |
| spellingShingle | Thaise Mayumi Taira Vítor Luís Ribeiro Yuri Jivago Silva Ribeiro Raquel Assed Bezerra da Silva Léa Assed Bezerra da Silva Marília Pacífico Lucisano Politi Lúcia Helena Faccioli Francisco Wanderley Garcia Paula-Silva Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice Data in Brief Arachidonic acid Leukotrienes Inflammation Bone resorption |
| title | Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice |
| title_full | Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice |
| title_fullStr | Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice |
| title_full_unstemmed | Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice |
| title_short | Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice |
| title_sort | gene expression data of inflammatory mediators in apical periodontitis in 129 wild type and 5 lipoxygenase knockout mice |
| topic | Arachidonic acid Leukotrienes Inflammation Bone resorption |
| url | http://www.sciencedirect.com/science/article/pii/S2352340921010611 |
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