Normal values of thyroid gland in Isfahan, an iodine replete area

<ul><li><strong>BACKGROUND</strong>: Because of different values of thyroid volume in different populations, and the effects of different trace element and geographic substances on thyroid volume, we decided to evaluate thyroid volume and its d...

Full description

Bibliographic Details
Main Authors: Atoosa Adibi, Mehri Sirous, Ashraf Aminorroaya, Ehsan Roohi, Mohsen Mostafavi, Zahra Fallah, Azamossadat Tabatabaei, Massoud Amini
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2008-04-01
Series:Journal of Research in Medical Sciences
Subjects:
Online Access:http://journals.mui.ac.ir/jrms/article/view/1375
_version_ 1818807626317692928
author Atoosa Adibi
Mehri Sirous
Ashraf Aminorroaya
Ehsan Roohi
Mohsen Mostafavi
Zahra Fallah
Azamossadat Tabatabaei
Massoud Amini
author_facet Atoosa Adibi
Mehri Sirous
Ashraf Aminorroaya
Ehsan Roohi
Mohsen Mostafavi
Zahra Fallah
Azamossadat Tabatabaei
Massoud Amini
author_sort Atoosa Adibi
collection DOAJ
description <ul><li><strong>BACKGROUND</strong>: Because of different values of thyroid volume in different populations, and the effects of different trace element and geographic substances on thyroid volume, we decided to evaluate thyroid volume and its determinants using ultrasound in healthy adults of Isfahan, a centrally located city in Iran, an iodine replete area.</li><li><strong>METHODS</strong>: In a cross-sectional study, 1500 healthy adults were enrolled by cluster sampling. Serum TSH level and morning urine iodine level were measured. Thyroid exam was performed according to WHO criteria and history of previous or present thyroid disease was taken. If all the mentioned results were normal they were considered clinically normal. One third of these normal subjects referred for thyroid ultrasonography. If ultrasonography of thyroid parenchyma texture was normal, and there was no nodule by sonography (thyroid incidentaloma), thyroid volume was measured using ellipsoid formula (X×Y×Z×8/6). Correlation between thyroid volume and age, sex, BMI, TSH level and urinary iodine concentration (UIC) was determined by Pearson correlation coefficient, t-Test and Kolmogorov-Smirnov. Thyroid volume more than 97% of this population was considered as goiter sonographically. Data expressed as mean ± SD, unless otherwise stated.</li><li><strong>RESULTS</strong>: We finally studied 200 subjects (123 Males, 77 females, average age: 37.27 ± 11.80 Years). The overall thyroid volume was 9.53 ± 3.68 ml. Males thyroid volume (10.73 ± 3.44 ml) was significantly higher than the females one (7.71 ± 2.63 ml) (P < 0.001). The thyroid volume ranges were 3-23.9 ml, 3.6-23.9 ml and 3-14.3 ml in all, males and females, respectively. Thyroid volume values more than 97 percentile of this reference range were 10.14 ml, 11.48 ml and 8.37 ml in all, males and females respectively, and were considered goiter sonographically. Thyroid volume had a positive correlation with age (r = 0.163, P = 0.022), but did not have correlation with serum TSH, UIC, and BMI, in both sexes. There was a strong correlation between thyroid volume, and height and body surface area (r = 0.48, P < 0.001).</li><li><strong>CONCLUSIONS</strong>: It was documented that thyroid volume is higher in male sex and increases with age, and have a positive correlation with body surface area and height.</li><li><strong>KEY WORDS</strong>: Adult, thyroid, ultrasonography, volume.</li></ul>
first_indexed 2024-12-18T19:28:39Z
format Article
id doaj.art-27ea4eae576147f8b52a38f8194080ef
institution Directory Open Access Journal
issn 1735-1995
1735-7136
language English
last_indexed 2024-12-18T19:28:39Z
publishDate 2008-04-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Research in Medical Sciences
spelling doaj.art-27ea4eae576147f8b52a38f8194080ef2022-12-21T20:55:47ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362008-04-011325560Normal values of thyroid gland in Isfahan, an iodine replete areaAtoosa AdibiMehri SirousAshraf AminorroayaEhsan RoohiMohsen MostafaviZahra FallahAzamossadat TabatabaeiMassoud Amini<ul><li><strong>BACKGROUND</strong>: Because of different values of thyroid volume in different populations, and the effects of different trace element and geographic substances on thyroid volume, we decided to evaluate thyroid volume and its determinants using ultrasound in healthy adults of Isfahan, a centrally located city in Iran, an iodine replete area.</li><li><strong>METHODS</strong>: In a cross-sectional study, 1500 healthy adults were enrolled by cluster sampling. Serum TSH level and morning urine iodine level were measured. Thyroid exam was performed according to WHO criteria and history of previous or present thyroid disease was taken. If all the mentioned results were normal they were considered clinically normal. One third of these normal subjects referred for thyroid ultrasonography. If ultrasonography of thyroid parenchyma texture was normal, and there was no nodule by sonography (thyroid incidentaloma), thyroid volume was measured using ellipsoid formula (X×Y×Z×8/6). Correlation between thyroid volume and age, sex, BMI, TSH level and urinary iodine concentration (UIC) was determined by Pearson correlation coefficient, t-Test and Kolmogorov-Smirnov. Thyroid volume more than 97% of this population was considered as goiter sonographically. Data expressed as mean ± SD, unless otherwise stated.</li><li><strong>RESULTS</strong>: We finally studied 200 subjects (123 Males, 77 females, average age: 37.27 ± 11.80 Years). The overall thyroid volume was 9.53 ± 3.68 ml. Males thyroid volume (10.73 ± 3.44 ml) was significantly higher than the females one (7.71 ± 2.63 ml) (P < 0.001). The thyroid volume ranges were 3-23.9 ml, 3.6-23.9 ml and 3-14.3 ml in all, males and females, respectively. Thyroid volume values more than 97 percentile of this reference range were 10.14 ml, 11.48 ml and 8.37 ml in all, males and females respectively, and were considered goiter sonographically. Thyroid volume had a positive correlation with age (r = 0.163, P = 0.022), but did not have correlation with serum TSH, UIC, and BMI, in both sexes. There was a strong correlation between thyroid volume, and height and body surface area (r = 0.48, P < 0.001).</li><li><strong>CONCLUSIONS</strong>: It was documented that thyroid volume is higher in male sex and increases with age, and have a positive correlation with body surface area and height.</li><li><strong>KEY WORDS</strong>: Adult, thyroid, ultrasonography, volume.</li></ul>http://journals.mui.ac.ir/jrms/article/view/1375Adult, thyroid, ultrasonography, volume.
spellingShingle Atoosa Adibi
Mehri Sirous
Ashraf Aminorroaya
Ehsan Roohi
Mohsen Mostafavi
Zahra Fallah
Azamossadat Tabatabaei
Massoud Amini
Normal values of thyroid gland in Isfahan, an iodine replete area
Journal of Research in Medical Sciences
Adult, thyroid, ultrasonography, volume.
title Normal values of thyroid gland in Isfahan, an iodine replete area
title_full Normal values of thyroid gland in Isfahan, an iodine replete area
title_fullStr Normal values of thyroid gland in Isfahan, an iodine replete area
title_full_unstemmed Normal values of thyroid gland in Isfahan, an iodine replete area
title_short Normal values of thyroid gland in Isfahan, an iodine replete area
title_sort normal values of thyroid gland in isfahan an iodine replete area
topic Adult, thyroid, ultrasonography, volume.
url http://journals.mui.ac.ir/jrms/article/view/1375
work_keys_str_mv AT atoosaadibi normalvaluesofthyroidglandinisfahananiodinerepletearea
AT mehrisirous normalvaluesofthyroidglandinisfahananiodinerepletearea
AT ashrafaminorroaya normalvaluesofthyroidglandinisfahananiodinerepletearea
AT ehsanroohi normalvaluesofthyroidglandinisfahananiodinerepletearea
AT mohsenmostafavi normalvaluesofthyroidglandinisfahananiodinerepletearea
AT zahrafallah normalvaluesofthyroidglandinisfahananiodinerepletearea
AT azamossadattabatabaei normalvaluesofthyroidglandinisfahananiodinerepletearea
AT massoudamini normalvaluesofthyroidglandinisfahananiodinerepletearea