Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore
Abstract Background Few studies have investigated physical activity (PA) and sedentary behavior (SB) in relation to fasting (FG) and 2-h postprandial plasma glucose (2hPG) levels and gestational diabetes mellitus (GDM); we investigated these associations among Asian pregnant women. Methods As part o...
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| Format: | Article |
| Language: | English |
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BMC
2017-10-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | http://link.springer.com/article/10.1186/s12884-017-1537-8 |
| _version_ | 1828431230750687232 |
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| author | Natarajan Padmapriya Jonathan Y. Bernard Shen Liang See Ling Loy Shirong Cai Iris Shen Zhe Kenneth Kwek Keith M. Godfrey Peter D. Gluckman Seang Mei Saw Yap-Seng Chong Jerry Kok Yen Chan Falk Müller-Riemenschneider on behalf of the GUSTO Study Group |
| author_facet | Natarajan Padmapriya Jonathan Y. Bernard Shen Liang See Ling Loy Shirong Cai Iris Shen Zhe Kenneth Kwek Keith M. Godfrey Peter D. Gluckman Seang Mei Saw Yap-Seng Chong Jerry Kok Yen Chan Falk Müller-Riemenschneider on behalf of the GUSTO Study Group |
| author_sort | Natarajan Padmapriya |
| collection | DOAJ |
| description | Abstract Background Few studies have investigated physical activity (PA) and sedentary behavior (SB) in relation to fasting (FG) and 2-h postprandial plasma glucose (2hPG) levels and gestational diabetes mellitus (GDM); we investigated these associations among Asian pregnant women. Methods As part of the Growing Up in Singapore Towards healthy Outcomes cohort study, PA and SB (sitting and television times) were assessed by interviewer-administered questionnaire. During 75 g oral glucose tolerance tests at 26–28 weeks’ gestation we measured FG, 2hPG levels and GDM (FG ≥ 7.0 mmol/L and/or 2hPG ≥ 7.8 mmol/L). Associations were analysed by multiple linear and logistic regression. Results Among the 1083 women studied, 18.6% had GDM. SB was not associated with FG, 2hPG and GDM. Higher categories of PA were associated with lower 2hPG and a lower likelihood of GDM (p-trend < 0.05), but not with FG levels. Compared to insufficiently active women, highly active women had lower 2hPG levels [β (95% CI): -0.32 (−0.59, −0.05), p = 0.020) and were less likely to have GDM [OR: 0.56 (0.32–0.98), p = 0.040]. Stratified analysis revealed no associations among under/normal-weight women, but significant associations among overweight/obese women; in those with BMI ≥23 kg/m2, sufficiently active and highly active women were less likely to have GDM [OR: 0.52, (0.29–0.93), p = 0.028, and OR: 0.34, (0.15–0.77), p = 0.010, respectively]. Conclusion Higher PA was associated with lower 2hPG levels and a lower prevalence of GDM, particularly in overweight/obese women. Further studies are warranted to confirm these findings, and to examine the effectiveness of PA promotion strategies for the prevention of gestational hyperglycemia. |
| first_indexed | 2024-12-10T18:00:58Z |
| format | Article |
| id | doaj.art-27ebfa268c7b4c638b92d5aac061def3 |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-12-10T18:00:58Z |
| publishDate | 2017-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-27ebfa268c7b4c638b92d5aac061def32022-12-22T01:38:47ZengBMCBMC Pregnancy and Childbirth1471-23932017-10-0117111010.1186/s12884-017-1537-8Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in SingaporeNatarajan Padmapriya0Jonathan Y. Bernard1Shen Liang2See Ling Loy3Shirong Cai4Iris Shen Zhe5Kenneth Kwek6Keith M. Godfrey7Peter D. Gluckman8Seang Mei Saw9Yap-Seng Chong10Jerry Kok Yen Chan11Falk Müller-Riemenschneider12on behalf of the GUSTO Study GroupDepartment of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of SingaporeSingapore Institute for Clinical Sciences, Agency for Science and Technology Research (A*STAR)Biostatistics Unit, Yong Loo Lin School of Medicine, National University of SingaporeKK Women’s and Children’s HospitalDepartment of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of SingaporeDepartment of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of SingaporeKK Women’s and Children’s HospitalMedical Research Council Lifecourse Epidemiology UnitSingapore Institute for Clinical Sciences, Agency for Science and Technology Research (A*STAR)Saw Swee Hock School of Public Health, National University of SingaporeDepartment of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of SingaporeKK Women’s and Children’s HospitalSaw Swee Hock School of Public Health, National University of SingaporeAbstract Background Few studies have investigated physical activity (PA) and sedentary behavior (SB) in relation to fasting (FG) and 2-h postprandial plasma glucose (2hPG) levels and gestational diabetes mellitus (GDM); we investigated these associations among Asian pregnant women. Methods As part of the Growing Up in Singapore Towards healthy Outcomes cohort study, PA and SB (sitting and television times) were assessed by interviewer-administered questionnaire. During 75 g oral glucose tolerance tests at 26–28 weeks’ gestation we measured FG, 2hPG levels and GDM (FG ≥ 7.0 mmol/L and/or 2hPG ≥ 7.8 mmol/L). Associations were analysed by multiple linear and logistic regression. Results Among the 1083 women studied, 18.6% had GDM. SB was not associated with FG, 2hPG and GDM. Higher categories of PA were associated with lower 2hPG and a lower likelihood of GDM (p-trend < 0.05), but not with FG levels. Compared to insufficiently active women, highly active women had lower 2hPG levels [β (95% CI): -0.32 (−0.59, −0.05), p = 0.020) and were less likely to have GDM [OR: 0.56 (0.32–0.98), p = 0.040]. Stratified analysis revealed no associations among under/normal-weight women, but significant associations among overweight/obese women; in those with BMI ≥23 kg/m2, sufficiently active and highly active women were less likely to have GDM [OR: 0.52, (0.29–0.93), p = 0.028, and OR: 0.34, (0.15–0.77), p = 0.010, respectively]. Conclusion Higher PA was associated with lower 2hPG levels and a lower prevalence of GDM, particularly in overweight/obese women. Further studies are warranted to confirm these findings, and to examine the effectiveness of PA promotion strategies for the prevention of gestational hyperglycemia.http://link.springer.com/article/10.1186/s12884-017-1537-8Physical activitySedentary behaviorGestational diabetes mellitusMaternal glucose levelsPregnancy |
| spellingShingle | Natarajan Padmapriya Jonathan Y. Bernard Shen Liang See Ling Loy Shirong Cai Iris Shen Zhe Kenneth Kwek Keith M. Godfrey Peter D. Gluckman Seang Mei Saw Yap-Seng Chong Jerry Kok Yen Chan Falk Müller-Riemenschneider on behalf of the GUSTO Study Group Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore BMC Pregnancy and Childbirth Physical activity Sedentary behavior Gestational diabetes mellitus Maternal glucose levels Pregnancy |
| title | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
| title_full | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
| title_fullStr | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
| title_full_unstemmed | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
| title_short | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
| title_sort | associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among asian women in singapore |
| topic | Physical activity Sedentary behavior Gestational diabetes mellitus Maternal glucose levels Pregnancy |
| url | http://link.springer.com/article/10.1186/s12884-017-1537-8 |
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