An improved reprogrammable mouse model harbouring the reverse tetracycline-controlled transcriptional transactivator 3
Reprogrammable mouse models engineered to conditionally express Oct-4, Klf-4, Sox-2 and c-Myc (OKSM) have been instrumental in dissecting molecular events underpinning the generation of induced pluripotent stem cells. However, until now these models have been reported in the context of the m2 revers...
Main Authors: | S. Alaei, A.S. Knaupp, S.M. Lim, J. Chen, M.L. Holmes, M.L. Änkö, C.M. Nefzger, J.M. Polo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-07-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S187350611630040X |
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