ABERRANT METHYLATION OF THE PROMOTER OF APC, CDH13 AND MGMT GENES IN COLORECTAL CANCER PATIENTS

ABERRANT METHYLATION OF THE PROMOTER OF APC, CDH13 AND MGMT GENES IN COLORECTAL CANCER PATIENTS

Aberrant methylation of gene promoter regions is the main epigenetic change characterizing colorectal cancer. Methylation levels of 42 CpG-sites of promoter regions of the MGMT, APC and CDH13 genes in colorectal cancer were studied in comparison with methylation levels of the adjacent normal tissue...

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Bibliographic Details
Main Authors: O. I. Kit, D. I. Vodolazhskiy, K. V. Dvadnenko, I. I. Efimova, E. N. Oleynikova, D. D. Oleynikov, N. N. Timoshkina
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2016-07-01
Series:Сибирский онкологический журнал
Subjects:
cpg-methylation
colorectal cancer
mgmt
apc
cdh13
cimp
Online Access:https://www.siboncoj.ru/jour/article/view/333

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