Emergence and circulation of azole-resistant C. albicans, C. auris and C. parapsilosis bloodstream isolates carrying Y132F, K143R or T220L Erg11p substitutions in Colombia

Emergence and circulation of azole-resistant C. albicans, C. auris and C. parapsilosis bloodstream isolates carrying Y132F, K143R or T220L Erg11p substitutions in Colombia

MethodsOver a four-year period, 123 Candida bloodstream isolates were collected at a quaternary care hospital. The isolates were identified by MALDI-TOF MS and their fluconazole (FLC) susceptibility patterns were assessed according to CLSI guidelines. Subsequently, sequencing of ERG11, TAC1 or MRR1,...

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Bibliographic Details
Main Authors: Andres Ceballos-Garzon, Ana Peñuela, Sandra Valderrama-Beltrán, Yerly Vargas-Casanova, Beatriz Ariza, Claudia M. Parra-Giraldo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Candida species
bloodstream infections
fluconazole resistance
ERG11
Y132F
Colombia
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1136217/full

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