Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 Patients
Purpose: Musculoskeletal (MSK) embolization is emerging in tendinopathy treatment. The objective of this study was to assess the efficacy and safety of MSK embolization with microspheres in the treatment of chronic shoulder pain. Patients and methods: This retrospective monocentric study included pa...
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MDPI AG
2022-03-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/4/744 |
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| author | Emeric Gremen Julien Frandon Gabriel Lateur Mathieu Finas Mathieu Rodière Clément Horteur Michaël Benassayag Frédéric Thony Régis Pailhe Julien Ghelfi |
| author_facet | Emeric Gremen Julien Frandon Gabriel Lateur Mathieu Finas Mathieu Rodière Clément Horteur Michaël Benassayag Frédéric Thony Régis Pailhe Julien Ghelfi |
| author_sort | Emeric Gremen |
| collection | DOAJ |
| description | Purpose: Musculoskeletal (MSK) embolization is emerging in tendinopathy treatment. The objective of this study was to assess the efficacy and safety of MSK embolization with microspheres in the treatment of chronic shoulder pain. Patients and methods: This retrospective monocentric study included patients with chronic shoulder pain resistant to 6 months or more of conventional therapies who were treated with MSK embolization between 2017 and 2021. Embolization was performed using calibrated 100–250 µm microspheres. Clinical success was defined as pain reduction, i.e., a decrease in the visual analogue scale (VAS) pain score of ≥50% at 3 months after MSK embolization as compared to baseline. Adverse events were collected. Results: Fifteen patients (11 women, 4 men) were included, with a median age of 50.3 years (IQR: 46.7–54.5). The median duration of symptoms was 26.6 months (20.6–39.8). The median VAS pain scores were 7.0 (7.0–8.0) at baseline, 6.0 (3.5–7.0) at 1 month, 5.0 (4.5–6.5) and 5.0 (3.0–7.4) at 3 months and 6 months (<i>p</i> = 0.002). Three patients (20%) reported clinical success at 3 months. Three patients experienced minor complications after embolization (paresthesia, <i>n</i> = 2; transient osteo-medullary edema, <i>n</i> = 1) and two patients had moderate complications (transient skin ischemia). Conclusion: MSK embolization with microspheres for treatment of refractory chronic shoulder pain showed moderate results in terms of clinical success and safety. |
| first_indexed | 2024-03-09T11:07:52Z |
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| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T11:07:52Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-27f38b2c221448739a61eff55475851a2023-12-01T00:52:41ZengMDPI AGBiomedicines2227-90592022-03-0110474410.3390/biomedicines10040744Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 PatientsEmeric Gremen0Julien Frandon1Gabriel Lateur2Mathieu Finas3Mathieu Rodière4Clément Horteur5Michaël Benassayag6Frédéric Thony7Régis Pailhe8Julien Ghelfi9Faculty of Medecine, Grenoble-Alpes University, 38043 Grenoble, FranceRadiology Department, Nimes University Hospital, University of Montpellier, 30900 Nimes, FranceOrthopaedic and Traumatology Surgery Department, Albertville Hospital, 73200 Albertville, FranceRadiology Department, Grenoble Alpes University Hospital, 38043 Grenoble, FranceRadiology Department, Grenoble Alpes University Hospital, 38043 Grenoble, FranceDepartment of Orthopaedic Surgery, Grenoble Alpes University Hospital, 38043 Grenoble, FranceOrthopaedic Surgery Department, Medipôle de Savoie Hospital, 73190 Challes-les-Eaux, FranceRadiology Department, Grenoble Alpes University Hospital, 38043 Grenoble, FranceFaculty of Medecine, Grenoble-Alpes University, 38043 Grenoble, FranceFaculty of Medecine, Grenoble-Alpes University, 38043 Grenoble, FrancePurpose: Musculoskeletal (MSK) embolization is emerging in tendinopathy treatment. The objective of this study was to assess the efficacy and safety of MSK embolization with microspheres in the treatment of chronic shoulder pain. Patients and methods: This retrospective monocentric study included patients with chronic shoulder pain resistant to 6 months or more of conventional therapies who were treated with MSK embolization between 2017 and 2021. Embolization was performed using calibrated 100–250 µm microspheres. Clinical success was defined as pain reduction, i.e., a decrease in the visual analogue scale (VAS) pain score of ≥50% at 3 months after MSK embolization as compared to baseline. Adverse events were collected. Results: Fifteen patients (11 women, 4 men) were included, with a median age of 50.3 years (IQR: 46.7–54.5). The median duration of symptoms was 26.6 months (20.6–39.8). The median VAS pain scores were 7.0 (7.0–8.0) at baseline, 6.0 (3.5–7.0) at 1 month, 5.0 (4.5–6.5) and 5.0 (3.0–7.4) at 3 months and 6 months (<i>p</i> = 0.002). Three patients (20%) reported clinical success at 3 months. Three patients experienced minor complications after embolization (paresthesia, <i>n</i> = 2; transient osteo-medullary edema, <i>n</i> = 1) and two patients had moderate complications (transient skin ischemia). Conclusion: MSK embolization with microspheres for treatment of refractory chronic shoulder pain showed moderate results in terms of clinical success and safety.https://www.mdpi.com/2227-9059/10/4/744chronic shoulder painembolizationmicrospheres |
| spellingShingle | Emeric Gremen Julien Frandon Gabriel Lateur Mathieu Finas Mathieu Rodière Clément Horteur Michaël Benassayag Frédéric Thony Régis Pailhe Julien Ghelfi Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 Patients Biomedicines chronic shoulder pain embolization microspheres |
| title | Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 Patients |
| title_full | Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 Patients |
| title_fullStr | Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 Patients |
| title_full_unstemmed | Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 Patients |
| title_short | Safety and Efficacy of Embolization with Microspheres in Chronic Refractory Inflammatory Shoulder Pain: A Pilot Monocentric Study on 15 Patients |
| title_sort | safety and efficacy of embolization with microspheres in chronic refractory inflammatory shoulder pain a pilot monocentric study on 15 patients |
| topic | chronic shoulder pain embolization microspheres |
| url | https://www.mdpi.com/2227-9059/10/4/744 |
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