Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication
Objective: Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2017-01-01
|
| Series: | Chinese Medical Journal |
| Subjects: | |
| Online Access: | http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=14;spage=1715;epage=1721;aulast=Xu |
| _version_ | 1818141154458206208 |
|---|---|
| author | Jing Xu Elan Yang Nan-Ze Yu Xiao Long |
| author_facet | Jing Xu Elan Yang Nan-Ze Yu Xiao Long |
| author_sort | Jing Xu |
| collection | DOAJ |
| description | Objective: Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors.
Data Sources: The data analyzed in this review were searched from articles included in PubMed and EMBASE databases.
Study Selection: The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review.
Results: The application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels.
Conclusions: Both past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction. |
| first_indexed | 2024-12-11T10:55:22Z |
| format | Article |
| id | doaj.art-27f5c4ab6290457e8f38fbc097eb29e1 |
| institution | Directory Open Access Journal |
| issn | 0366-6999 |
| language | English |
| last_indexed | 2024-12-11T10:55:22Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Chinese Medical Journal |
| spelling | doaj.art-27f5c4ab6290457e8f38fbc097eb29e12022-12-22T01:10:06ZengWolters KluwerChinese Medical Journal0366-69992017-01-01130141715172110.4103/0366-6999.209896Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and ComplicationJing XuElan YangNan-Ze YuXiao LongObjective: Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors. Data Sources: The data analyzed in this review were searched from articles included in PubMed and EMBASE databases. Study Selection: The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review. Results: The application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels. Conclusions: Both past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction.http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=14;spage=1715;epage=1721;aulast=XuCombination Therapy; Keloids; Radiation Therapy |
| spellingShingle | Jing Xu Elan Yang Nan-Ze Yu Xiao Long Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication Chinese Medical Journal Combination Therapy; Keloids; Radiation Therapy |
| title | Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication |
| title_full | Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication |
| title_fullStr | Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication |
| title_full_unstemmed | Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication |
| title_short | Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication |
| title_sort | radiation therapy in keloids treatment history strategy effectiveness and complication |
| topic | Combination Therapy; Keloids; Radiation Therapy |
| url | http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=14;spage=1715;epage=1721;aulast=Xu |
| work_keys_str_mv | AT jingxu radiationtherapyinkeloidstreatmenthistorystrategyeffectivenessandcomplication AT elanyang radiationtherapyinkeloidstreatmenthistorystrategyeffectivenessandcomplication AT nanzeyu radiationtherapyinkeloidstreatmenthistorystrategyeffectivenessandcomplication AT xiaolong radiationtherapyinkeloidstreatmenthistorystrategyeffectivenessandcomplication |