Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell Lymphoma
Non-Hodgkin’s B-cell lymphoma is a hematological condition with different types based on clinical presentation, pathological features, and therapeutic response, like Diffuse Large B-cell Lymphoma (DLBCL), follicular lymphoma, and Chronic Lymphocytic Leukemia (CLL). We report A 33-year-old male prese...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2021-05-01
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| Series: | Case Reports in Clinical Practice |
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| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/349 |
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| author | Sepehr Sahraiyan Mahsa Abbaszadeh Pouyan Aminishakib Rastegar Rahmani Tanha Sahar Karimpour Reyhan |
| author_facet | Sepehr Sahraiyan Mahsa Abbaszadeh Pouyan Aminishakib Rastegar Rahmani Tanha Sahar Karimpour Reyhan |
| author_sort | Sepehr Sahraiyan |
| collection | DOAJ |
| description | Non-Hodgkin’s B-cell lymphoma is a hematological condition with different types based on clinical presentation, pathological features, and therapeutic response, like Diffuse Large B-cell Lymphoma (DLBCL), follicular lymphoma, and Chronic Lymphocytic Leukemia (CLL). We report A 33-year-old male presented with a complaint of unilateral leg swelling, firstly supposed to be a Deep Vein Thrombosis (DVT); however, in multiple Doppler ultrasonography, DVT was ruled out. The patient’s precise history revealed a swollen mass in the left knee region for two months that slowly enlarged and was confirmed with a physical examination. Doppler ultrasonography of the lower extremities conducted in our center presented no sign of deep vein thrombosis; however, it demonstrated some complex conglomerate lymph nodes in the left inguinal compressing the ipsilateral femoral and iliac vein. It also revealed bulky adenopathy, with a 95×65 mm left knee mass. The performed biopsy reported the existence of malignant lymphoma, suggesting the existence of DLBCL. Consequently, he was referred to a hematology/oncology department for appropriate treatment. This unusual presentation of DLBCL and the importance of noticing an accurate history taking and physical examination, instead of conducting unnecessary paraclinical tests (several Doppler ultrasonography in this case), have led us to report this case. |
| first_indexed | 2024-12-14T07:03:16Z |
| format | Article |
| id | doaj.art-27f6ffbb63104b4093dce5251c068b42 |
| institution | Directory Open Access Journal |
| issn | 2538-2683 2538-2691 |
| language | English |
| last_indexed | 2024-12-14T07:03:16Z |
| publishDate | 2021-05-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Case Reports in Clinical Practice |
| spelling | doaj.art-27f6ffbb63104b4093dce5251c068b422022-12-21T23:12:21ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912021-05-016110.18502/crcp.v6i1.5953Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell LymphomaSepehr Sahraiyan0Mahsa Abbaszadeh1Pouyan Aminishakib2Rastegar Rahmani Tanha3Sahar Karimpour Reyhan4Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.Department of Oral and Maxillofacial Pathology, Tehran University of Medical Sciences, Tehran, Iran.Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.Non-Hodgkin’s B-cell lymphoma is a hematological condition with different types based on clinical presentation, pathological features, and therapeutic response, like Diffuse Large B-cell Lymphoma (DLBCL), follicular lymphoma, and Chronic Lymphocytic Leukemia (CLL). We report A 33-year-old male presented with a complaint of unilateral leg swelling, firstly supposed to be a Deep Vein Thrombosis (DVT); however, in multiple Doppler ultrasonography, DVT was ruled out. The patient’s precise history revealed a swollen mass in the left knee region for two months that slowly enlarged and was confirmed with a physical examination. Doppler ultrasonography of the lower extremities conducted in our center presented no sign of deep vein thrombosis; however, it demonstrated some complex conglomerate lymph nodes in the left inguinal compressing the ipsilateral femoral and iliac vein. It also revealed bulky adenopathy, with a 95×65 mm left knee mass. The performed biopsy reported the existence of malignant lymphoma, suggesting the existence of DLBCL. Consequently, he was referred to a hematology/oncology department for appropriate treatment. This unusual presentation of DLBCL and the importance of noticing an accurate history taking and physical examination, instead of conducting unnecessary paraclinical tests (several Doppler ultrasonography in this case), have led us to report this case.https://crcp.tums.ac.ir/index.php/crcp/article/view/349EdemaLymphomaSwellingDiffuse large B-cell lymphomaLymphadenopathyVenous thrombosis |
| spellingShingle | Sepehr Sahraiyan Mahsa Abbaszadeh Pouyan Aminishakib Rastegar Rahmani Tanha Sahar Karimpour Reyhan Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell Lymphoma Case Reports in Clinical Practice Edema Lymphoma Swelling Diffuse large B-cell lymphoma Lymphadenopathy Venous thrombosis |
| title | Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell Lymphoma |
| title_full | Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell Lymphoma |
| title_fullStr | Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell Lymphoma |
| title_full_unstemmed | Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell Lymphoma |
| title_short | Unilateral Lower Extremity Swelling as an Unusual Presentaton of Non-Hodgkin’s B-Cell Lymphoma |
| title_sort | unilateral lower extremity swelling as an unusual presentaton of non hodgkin s b cell lymphoma |
| topic | Edema Lymphoma Swelling Diffuse large B-cell lymphoma Lymphadenopathy Venous thrombosis |
| url | https://crcp.tums.ac.ir/index.php/crcp/article/view/349 |
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