Disrupting ACE2 Dimerization Mitigates the Infection by SARS-CoV-2 Pseudovirus

Disrupting ACE2 Dimerization Mitigates the Infection by SARS-CoV-2 Pseudovirus

The coronavirus disease 2019 pandemic has caused over million death and 500 million reported cases globally. More effective antiviral medications are needed to curb the continued spread of this disease. The infection by SARS-CoV-2 virus is initiated via the interaction between the receptor binding d...

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Bibliographic Details
Main Authors: Jiaqi Zhu, Yue Su, Young Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Virology
Subjects:
ACE2
S protein
dimerization
protein–protein interaction
peptides
BiFC
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.916700/full

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