Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients

Sudden cardiac death (SCD) remains the principal cause of coronary heart disease (CHD) deaths. Therefore, studying SCD mechanisms, implementing new prognostic and preventive approaches are the main aims of modern cardiology. The review analyzes modern approaches to myocardial electrical instability...

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Main Authors: V. V. Popov, A. E. Radzevich
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2007-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1272
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author V. V. Popov
A. E. Radzevich
author_facet V. V. Popov
A. E. Radzevich
author_sort V. V. Popov
collection DOAJ
description Sudden cardiac death (SCD) remains the principal cause of coronary heart disease (CHD) deaths. Therefore, studying SCD mechanisms, implementing new prognostic and preventive approaches are the main aims of modern cardiology. The review analyzes modern approaches to myocardial electrical instability correction and prognosis improvement in CHD patients. It has been proved that among all antiarrhythmics, beta-adrenoblockers only, and perhaps amiodaron, can reduce SCD incidence. Total mortality and SCD rate reduction has been demonstrated for ACE inhibitors, aspirin, statins, aldosterone antagonists. Recent clinical trials have proved that implanted cardioverters-defibrillators are more effective than pharmaceutical treatment in SCD prevention among high-risk patients.
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spelling doaj.art-27f9a18858394b828cfe5d729b66aa6e2023-03-13T07:23:14Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252007-06-0163106115983Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patientsV. V. Popov0A. E. Radzevich1Московский государственный медико-стоматологический университет на базе Центральной больницы № 6 «ОАО» РЖД, МоскваМосковский государственный медико-стоматологический университет на базе Центральной больницы № 6 «ОАО» РЖД, МоскваSudden cardiac death (SCD) remains the principal cause of coronary heart disease (CHD) deaths. Therefore, studying SCD mechanisms, implementing new prognostic and preventive approaches are the main aims of modern cardiology. The review analyzes modern approaches to myocardial electrical instability correction and prognosis improvement in CHD patients. It has been proved that among all antiarrhythmics, beta-adrenoblockers only, and perhaps amiodaron, can reduce SCD incidence. Total mortality and SCD rate reduction has been demonstrated for ACE inhibitors, aspirin, statins, aldosterone antagonists. Recent clinical trials have proved that implanted cardioverters-defibrillators are more effective than pharmaceutical treatment in SCD prevention among high-risk patients.https://cardiovascular.elpub.ru/jour/article/view/1272ишемическая болезнь сердцажизнеугрожающие аритмиивнезапная сердечная смертьβ-адреноблокаторыингибиторы ангиотензин-превращающего ферментаимплантируемые кардиовертеры-дефибрилляторы
spellingShingle V. V. Popov
A. E. Radzevich
Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
Кардиоваскулярная терапия и профилактика
ишемическая болезнь сердца
жизнеугрожающие аритмии
внезапная сердечная смерть
β-адреноблокаторы
ингибиторы ангиотензин-превращающего фермента
имплантируемые кардиовертеры-дефибрилляторы
title Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
title_full Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
title_fullStr Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
title_full_unstemmed Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
title_short Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
title_sort modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
topic ишемическая болезнь сердца
жизнеугрожающие аритмии
внезапная сердечная смерть
β-адреноблокаторы
ингибиторы ангиотензин-превращающего фермента
имплантируемые кардиовертеры-дефибрилляторы
url https://cardiovascular.elpub.ru/jour/article/view/1272
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