Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic finding
A woman (70-years) with a history of iron deficiency anemia and chronic kidney disease presented with two weeks of abdominal pain. Upper endoscopy demonstrated the gastric and duodenal mucosa was black and speckled consistent with diagnosis...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2014-06-01
|
| Series: | Endoscopy International Open |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1377175 |
| Summary: | A woman (70-years) with a history of iron deficiency anemia and chronic kidney
disease presented with two weeks of abdominal pain. Upper endoscopy demonstrated
the gastric and duodenal mucosa was black and speckled consistent with diagnosis
of pseudomelanosis. Biopsies showed pigment-laden macrophages in the lamina
propria, which stained positive for iron and Masson-Fontana trichrome stain
consistent with a “melanin-like” pigment. Although an uncommon endoscopic
finding, this pigment has been associated with the use of certain medications,
antihypertensives and iron supplements, and systemic illnesses, including
hypertension, chronic kidney disease, gastric hemorrhage, and diabetes mellitus. |
|---|---|
| ISSN: | 2364-3722 2196-9736 |