Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic finding
A woman (70-years) with a history of iron deficiency anemia and chronic kidney disease presented with two weeks of abdominal pain. Upper endoscopy demonstrated the gastric and duodenal mucosa was black and speckled consistent with diagnosis...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2014-06-01
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| Series: | Endoscopy International Open |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1377175 |
| _version_ | 1811289732955504640 |
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| author | M. Thure Caire Shivam Kalan Patrick Brady Jeffrey Gill |
| author_facet | M. Thure Caire Shivam Kalan Patrick Brady Jeffrey Gill |
| author_sort | M. Thure Caire |
| collection | DOAJ |
| description | A woman (70-years) with a history of iron deficiency anemia and chronic kidney
disease presented with two weeks of abdominal pain. Upper endoscopy demonstrated
the gastric and duodenal mucosa was black and speckled consistent with diagnosis
of pseudomelanosis. Biopsies showed pigment-laden macrophages in the lamina
propria, which stained positive for iron and Masson-Fontana trichrome stain
consistent with a “melanin-like” pigment. Although an uncommon endoscopic
finding, this pigment has been associated with the use of certain medications,
antihypertensives and iron supplements, and systemic illnesses, including
hypertension, chronic kidney disease, gastric hemorrhage, and diabetes mellitus. |
| first_indexed | 2024-04-13T03:59:38Z |
| format | Article |
| id | doaj.art-27fc6ae1b80647e489c8bc0d652c0b4b |
| institution | Directory Open Access Journal |
| issn | 2364-3722 2196-9736 |
| language | English |
| last_indexed | 2024-04-13T03:59:38Z |
| publishDate | 2014-06-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Endoscopy International Open |
| spelling | doaj.art-27fc6ae1b80647e489c8bc0d652c0b4b2022-12-22T03:03:30ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362014-06-010203E191E19210.1055/s-0034-1377175Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic findingM. Thure Caire0Shivam Kalan1Patrick Brady2Jeffrey Gill3University of South Florida Health, Morsani College of Medicine, Department of Gastroenterology University of South Florida Health, Morsani College of Medicine, Department of Internal MedicineUniversity of South Florida Health, Morsani College of Medicine, Department of Gastroenterology James A. Haley Veterans Hospital, Department of GastroenterologyA woman (70-years) with a history of iron deficiency anemia and chronic kidney disease presented with two weeks of abdominal pain. Upper endoscopy demonstrated the gastric and duodenal mucosa was black and speckled consistent with diagnosis of pseudomelanosis. Biopsies showed pigment-laden macrophages in the lamina propria, which stained positive for iron and Masson-Fontana trichrome stain consistent with a “melanin-like” pigment. Although an uncommon endoscopic finding, this pigment has been associated with the use of certain medications, antihypertensives and iron supplements, and systemic illnesses, including hypertension, chronic kidney disease, gastric hemorrhage, and diabetes mellitus.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1377175 |
| spellingShingle | M. Thure Caire Shivam Kalan Patrick Brady Jeffrey Gill Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic finding Endoscopy International Open |
| title | Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic
finding |
| title_full | Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic
finding |
| title_fullStr | Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic
finding |
| title_full_unstemmed | Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic
finding |
| title_short | Pseudomelanosis of the stomach and duodenum: an uncommon endoscopic
finding |
| title_sort | pseudomelanosis of the stomach and duodenum an uncommon endoscopic finding |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1377175 |
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