Repurposing antimalarial artesunate for the prophylactic treatment of depression: Evidence from preclinical research

Repurposing antimalarial artesunate for the prophylactic treatment of depression: Evidence from preclinical research

Abstract Introduction Several studies have linked inflammation and oxidative stress with the pathogenesis of depression. Artesunate is a commonly used medication to treat malaria and has been shown to produce antioxidant, anti‐inflammatory, and immunomodulatory effects. However, its prophylactic eff...

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Bibliographic Details
Main Authors: Shihao Huang, Ewa Galaj, Jinfeng Wang, Yi Guo, Shuang Wang, Mengxu Shi, Xueyong Yin, Keyao Liu, Yixiao Luo, Li Meng, Haishui Shi
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Brain and Behavior
Subjects:
artesunate
depression
inflammation
lipopolysaccharide
mouse
Online Access:https://doi.org/10.1002/brb3.2833

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