Noninfectious pulmonary complications of haematopoietic stem cell transplantation
Haematopoietic stem cell transplantation (HSCT) is an established treatment for a variety of malignant and nonmalignant conditions. Pulmonary complications, both infectious and noninfectious, are a major cause of morbidity and mortality in patients who undergo HSCT. Recent advances in prophylaxis an...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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European Respiratory Society
2020-06-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/29/156/190119.full |
| _version_ | 1818773086912118784 |
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| author | Samran Haider Navin Durairajan Ayman O. Soubani |
| author_facet | Samran Haider Navin Durairajan Ayman O. Soubani |
| author_sort | Samran Haider |
| collection | DOAJ |
| description | Haematopoietic stem cell transplantation (HSCT) is an established treatment for a variety of malignant and nonmalignant conditions. Pulmonary complications, both infectious and noninfectious, are a major cause of morbidity and mortality in patients who undergo HSCT. Recent advances in prophylaxis and treatment of infectious complications has increased the significance of noninfectious pulmonary conditions. Acute lung injury associated with idiopathic pneumonia syndrome remains a major acute complication with high morbidity and mortality. On the other hand, bronchiolitis obliterans syndrome is the most challenging chronic pulmonary complication facing clinicians who are taking care of allogeneic HSCT recipients. Other noninfectious pulmonary complications following HSCT are less frequent. This review provides a clinical update of the incidence, risk factors, pathogenesis, clinical characteristics and management of the main noninfectious pulmonary complications following HSCT. |
| first_indexed | 2024-12-18T10:19:40Z |
| format | Article |
| id | doaj.art-27fe232c59894d828c217a5672edf14c |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-12-18T10:19:40Z |
| publishDate | 2020-06-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-27fe232c59894d828c217a5672edf14c2022-12-21T21:11:10ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172020-06-012915610.1183/16000617.0119-20190119-2019Noninfectious pulmonary complications of haematopoietic stem cell transplantationSamran Haider0Navin Durairajan1Ayman O. Soubani2 Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University School of Medicine, Detroit, MI, USA Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University School of Medicine, Detroit, MI, USA Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University School of Medicine, Detroit, MI, USA Haematopoietic stem cell transplantation (HSCT) is an established treatment for a variety of malignant and nonmalignant conditions. Pulmonary complications, both infectious and noninfectious, are a major cause of morbidity and mortality in patients who undergo HSCT. Recent advances in prophylaxis and treatment of infectious complications has increased the significance of noninfectious pulmonary conditions. Acute lung injury associated with idiopathic pneumonia syndrome remains a major acute complication with high morbidity and mortality. On the other hand, bronchiolitis obliterans syndrome is the most challenging chronic pulmonary complication facing clinicians who are taking care of allogeneic HSCT recipients. Other noninfectious pulmonary complications following HSCT are less frequent. This review provides a clinical update of the incidence, risk factors, pathogenesis, clinical characteristics and management of the main noninfectious pulmonary complications following HSCT.http://err.ersjournals.com/content/29/156/190119.full |
| spellingShingle | Samran Haider Navin Durairajan Ayman O. Soubani Noninfectious pulmonary complications of haematopoietic stem cell transplantation European Respiratory Review |
| title | Noninfectious pulmonary complications of haematopoietic stem cell transplantation |
| title_full | Noninfectious pulmonary complications of haematopoietic stem cell transplantation |
| title_fullStr | Noninfectious pulmonary complications of haematopoietic stem cell transplantation |
| title_full_unstemmed | Noninfectious pulmonary complications of haematopoietic stem cell transplantation |
| title_short | Noninfectious pulmonary complications of haematopoietic stem cell transplantation |
| title_sort | noninfectious pulmonary complications of haematopoietic stem cell transplantation |
| url | http://err.ersjournals.com/content/29/156/190119.full |
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