Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic Review
Antimicrobial resistance is a growing public health crisis, propelled by inappropriate antibiotic prescription, in particular the over-prescription of antibiotics, prolonged duration of antibiotic therapy and the overuse of broad-spectrum antibiotics. The paediatric population, in particular, those...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/8/1226 |
| _version_ | 1797432280010981376 |
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| author | Keshani Weragama Poonam Mudgil John Whitehall |
| author_facet | Keshani Weragama Poonam Mudgil John Whitehall |
| author_sort | Keshani Weragama |
| collection | DOAJ |
| description | Antimicrobial resistance is a growing public health crisis, propelled by inappropriate antibiotic prescription, in particular the over-prescription of antibiotics, prolonged duration of antibiotic therapy and the overuse of broad-spectrum antibiotics. The paediatric population, in particular, those presenting to emergency settings with respiratory symptoms, have been associated with a high rate of antibiotic prescription rates. Further research has now shown that many of these antibiotic prescriptions may have been avoided, with more targeted diagnostic methods to identify underlying aetiologies. The purpose of this systematic review was to assess the impact of rapid diagnostic testing, for paediatric respiratory presentations in the emergency setting, on antibiotic prescription rates. To review the relevant history, a comprehensive search of Medline, EMBASE and Cochrane Database of Systematic Reviews was performed. Eighteen studies were included in the review, and these studies assessed a variety of rapid diagnostic testing tools and outcome measures. Overall, rapid diagnostic testing was found to be an effective method of diagnostic antibiotic stewardship with great promise in improving antibiotic prescribing behaviours. Further studies are required to evaluate the use of rapid diagnostic testing with other methods of antibiotics stewardship, including clinical decisions aids and to increase the specificity of interventions following diagnosis to further reduce rates of antibiotic prescription. |
| first_indexed | 2024-03-09T09:59:05Z |
| format | Article |
| id | doaj.art-27ffc42ba6cf418395a8c2d33c692f84 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T09:59:05Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-27ffc42ba6cf418395a8c2d33c692f842023-12-01T23:34:25ZengMDPI AGChildren2227-90672022-08-0198122610.3390/children9081226Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic ReviewKeshani Weragama0Poonam Mudgil1John Whitehall2Department of Paediatrics, School of Medicine, Western Sydney University, Campbelltown, NSW 2560, AustraliaDepartment of Paediatrics, School of Medicine, Western Sydney University, Campbelltown, NSW 2560, AustraliaDepartment of Paediatrics, School of Medicine, Western Sydney University, Campbelltown, NSW 2560, AustraliaAntimicrobial resistance is a growing public health crisis, propelled by inappropriate antibiotic prescription, in particular the over-prescription of antibiotics, prolonged duration of antibiotic therapy and the overuse of broad-spectrum antibiotics. The paediatric population, in particular, those presenting to emergency settings with respiratory symptoms, have been associated with a high rate of antibiotic prescription rates. Further research has now shown that many of these antibiotic prescriptions may have been avoided, with more targeted diagnostic methods to identify underlying aetiologies. The purpose of this systematic review was to assess the impact of rapid diagnostic testing, for paediatric respiratory presentations in the emergency setting, on antibiotic prescription rates. To review the relevant history, a comprehensive search of Medline, EMBASE and Cochrane Database of Systematic Reviews was performed. Eighteen studies were included in the review, and these studies assessed a variety of rapid diagnostic testing tools and outcome measures. Overall, rapid diagnostic testing was found to be an effective method of diagnostic antibiotic stewardship with great promise in improving antibiotic prescribing behaviours. Further studies are required to evaluate the use of rapid diagnostic testing with other methods of antibiotics stewardship, including clinical decisions aids and to increase the specificity of interventions following diagnosis to further reduce rates of antibiotic prescription.https://www.mdpi.com/2227-9067/9/8/1226antibioticsantimicrobial resistancepaediatricsrapid diagnostic testingdiagnostic antibiotic stewardshiprespiratory tract infections |
| spellingShingle | Keshani Weragama Poonam Mudgil John Whitehall Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic Review Children antibiotics antimicrobial resistance paediatrics rapid diagnostic testing diagnostic antibiotic stewardship respiratory tract infections |
| title | Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic Review |
| title_full | Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic Review |
| title_fullStr | Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic Review |
| title_full_unstemmed | Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic Review |
| title_short | Diagnostic Stewardship—The Impact of Rapid Diagnostic Testing for Paediatric Respiratory Presentations in the Emergency Setting: A Systematic Review |
| title_sort | diagnostic stewardship the impact of rapid diagnostic testing for paediatric respiratory presentations in the emergency setting a systematic review |
| topic | antibiotics antimicrobial resistance paediatrics rapid diagnostic testing diagnostic antibiotic stewardship respiratory tract infections |
| url | https://www.mdpi.com/2227-9067/9/8/1226 |
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