CRISISS: A Novel, Transcriptionally and Post-Translationally Inducible CRISPR/Cas9-Based Cellular Suicide Switch

CRISISS: A Novel, Transcriptionally and Post-Translationally Inducible CRISPR/Cas9-Based Cellular Suicide Switch

With the ever-increasing developing rate of gene and cellular therapy applications and growing accessibility due to products receiving regulatory approval, the need for effective and reliable safety mechanisms to prevent or eliminate potentially fatal side effects is of the utmost importance. In thi...

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Bibliographic Details
Main Authors: Maximilian Amberger, Esther Grueso, Zoltán Ivics
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
suicide switch
suicide gene
CRISPR/Cas9
<i>Alu</i> retrotransposon
<i>Sleeping Beauty</i> transposon
gene therapy
Online Access:https://www.mdpi.com/1422-0067/24/12/9799

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