Bacterial Heat-Stable Enterotoxins: Translation of Pathogenic Peptides into Novel Targeted Diagnostics and Therapeutics
Heat-stable toxins (STs) produced by enterotoxigenic bacteria cause endemic and traveler’s diarrhea by binding to and activating the intestinal receptor guanylyl cyclase C (GC-C). Advances in understanding the biology of GC-C have extended ST from a diarrheagenic peptide to a novel therapeutic agent...
Main Authors: | Chang Chang, Brian A. Stoecker, Adam E. Snook, Peng Li, Michael S. Magee, Glen Marszalowicz, Michael Valentino, Jieru E. Lin, Scott A. Waldman |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-08-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/2/8/2028/ |
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