Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report
Abstract INTRODUCTION: The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG anti...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200231&lng=en&tlng=en |
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| author | Claudia Machicado Stéphane Bertani Patricia Herrera-Velit Jose Espinoza Eloy Ruiz Luis Marcos |
| author_facet | Claudia Machicado Stéphane Bertani Patricia Herrera-Velit Jose Espinoza Eloy Ruiz Luis Marcos |
| author_sort | Claudia Machicado |
| collection | DOAJ |
| description | Abstract INTRODUCTION: The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. METHODS In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. RESULTS Fas2-ELISA demonstrated negative results in all HCC patients included in this study. CONCLUSIONS The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies. |
| first_indexed | 2024-04-12T18:03:04Z |
| format | Article |
| id | doaj.art-28074fae6b3d453e8d620c7226833086 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T18:03:04Z |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-28074fae6b3d453e8d620c72268330862022-12-22T03:22:04ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-984951223123310.1590/0037-8682-0180-2017S0037-86822018000200231Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary reportClaudia MachicadoStéphane BertaniPatricia Herrera-VelitJose EspinozaEloy RuizLuis MarcosAbstract INTRODUCTION: The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. METHODS In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. RESULTS Fas2-ELISA demonstrated negative results in all HCC patients included in this study. CONCLUSIONS The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200231&lng=en&tlng=enCholangiocarcinomaFasciolosisFibrosisHepatocellular carcinomaLiver fluke |
| spellingShingle | Claudia Machicado Stéphane Bertani Patricia Herrera-Velit Jose Espinoza Eloy Ruiz Luis Marcos Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report Revista da Sociedade Brasileira de Medicina Tropical Cholangiocarcinoma Fasciolosis Fibrosis Hepatocellular carcinoma Liver fluke |
| title | Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report |
| title_full | Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report |
| title_fullStr | Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report |
| title_full_unstemmed | Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report |
| title_short | Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report |
| title_sort | negative serology of fasciola hepatica infection in patients with liver cancer in peru a preliminary report |
| topic | Cholangiocarcinoma Fasciolosis Fibrosis Hepatocellular carcinoma Liver fluke |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200231&lng=en&tlng=en |
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