Efficacy of various herbal preparations against oral Candida: A lab-based study

Aim: This research was done to analyze the effectiveness related to herbal chemicals in tackling candidiasis. Materials and Methods: Grounded and ethanol-extracted residues of plants like Avicennia marina, Fagonia indica, Portulaca oleracea, Lawsania inermis, Ziziphus spina, Asphodelus tenuifolius,...

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Bibliographic Details
Main Authors: Prashant A Karni, Aparna Muraleedharan, Srikala Bhandary, Sheetal Mujoo, Anuj Paul Maini, Mudita Chaturvedi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=265;epage=267;aulast=Karni
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Summary:Aim: This research was done to analyze the effectiveness related to herbal chemicals in tackling candidiasis. Materials and Methods: Grounded and ethanol-extracted residues of plants like Avicennia marina, Fagonia indica, Portulaca oleracea, Lawsania inermis, Ziziphus spina, Asphodelus tenuifolius, and Salvadora persica were used in the study. The extract was used against candida species, after which the antibacterial as well as cytotoxicity toward the former were evaluated. Results: L. inermis and P. oleracea with minimal inhibitory concentration of approx. 10 cenmL had an increased activity against candida species. The preparations of these plants acted against Candida albicans during its stages related to pathogenesis during biofilm production. Superadded infections like in case of bacterial infections along with candida can be difficult to cure. On human RBCs, these plant preparations had no toxicity at their minimum inhibitory concentration level. Conclusion: We concluded that, as far as being anti-candida and acting against MDR bacterial infections, preparations of plants were effective as an alternative to allopathic drugs.
ISSN:0975-7406