Gut microbiota dysbiosis and decreased levels of acetic and propionic acid participate in glucocorticoid-induced glycolipid metabolism disorder

Gut microbiota dysbiosis and decreased levels of acetic and propionic acid participate in glucocorticoid-induced glycolipid metabolism disorder

ABSTRACTLong-term/high-dose glucocorticoid (GC) use results in glycolipid metabolism disorder, which severely limits its clinical application. The role of the gut microbiota and its metabolites in GC-induced glycolipid metabolism disorder remains unclear. Our previous human study found that obvious...

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Bibliographic Details
Main Authors: Qin Zhang, Gaopeng Guan, Jie Liu, Wenmu Hu, Ping Jin
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mBio
Subjects:
gut microbiota
glucocorticoids
SCFAs
glycolipid metabolism
Online Access:https://journals.asm.org/doi/10.1128/mbio.02943-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02943-23

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