Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic study
Objective: Simvastatin was used as an adjuvant medication in this clinico-radiographic investigation to assess the impact on crestal bone levels around immediate implantation. Materials and Methods: A randomized controlled trial with 50 patients who needed an implant placed right away was done. Simv...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=279;epage=282;aulast=Betha |
| _version_ | 1797222299060928512 |
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| author | Hymasre Betha M Rajmohan Radhika Thakkar Bezgam R Surya Manoj Shetty Puja Sankla Rahul Tiwari |
| author_facet | Hymasre Betha M Rajmohan Radhika Thakkar Bezgam R Surya Manoj Shetty Puja Sankla Rahul Tiwari |
| author_sort | Hymasre Betha |
| collection | DOAJ |
| description | Objective: Simvastatin was used as an adjuvant medication in this clinico-radiographic investigation to assess the impact on crestal bone levels around immediate implantation. Materials and Methods: A randomized controlled trial with 50 patients who needed an implant placed right away was done. Simvastatin was used as an adjuvant in groups ((Group A), whereas group (Group B)) served as the control group for the participants. At baseline and during follow-up visits, clinical measures such as probing depth (PD) and bleeding on probing (BOP) were measured. At baseline and 12 weeks, radiographic measurements of crestal bone levels were taken. Results: At 12 weeks, Group A demonstrated a significantly lower PD and BOP than did Group B. Furthermore, at 12 weeks, Group A showed greater crestal bone preservation than did Group B. The results of the statistical analysis showed that the two groups were significantly different. Conclusion: The results of this study indicate that simvastatin use as an adjuvant medication after immediate implant insertion contributes to better clinical outcomes and greater crestal bone preservation. Simvastatin may be helpful in increasing bone regeneration, decreasing inflammation, and soft tissue healing. These findings demonstrate how simvastatin may be used as an additional therapy to enhance the effectiveness of rapid implant implantation operations. |
| first_indexed | 2024-04-24T13:19:07Z |
| format | Article |
| id | doaj.art-280fc23c7169433ea2d1f36dfbaaf6d3 |
| institution | Directory Open Access Journal |
| issn | 0975-7406 |
| language | English |
| last_indexed | 2024-04-24T13:19:07Z |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj.art-280fc23c7169433ea2d1f36dfbaaf6d32024-04-04T16:37:39ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062024-01-0116527928210.4103/jpbs.jpbs_492_23Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic studyHymasre BethaM RajmohanRadhika ThakkarBezgam R SuryaManoj ShettyPuja SanklaRahul TiwariObjective: Simvastatin was used as an adjuvant medication in this clinico-radiographic investigation to assess the impact on crestal bone levels around immediate implantation. Materials and Methods: A randomized controlled trial with 50 patients who needed an implant placed right away was done. Simvastatin was used as an adjuvant in groups ((Group A), whereas group (Group B)) served as the control group for the participants. At baseline and during follow-up visits, clinical measures such as probing depth (PD) and bleeding on probing (BOP) were measured. At baseline and 12 weeks, radiographic measurements of crestal bone levels were taken. Results: At 12 weeks, Group A demonstrated a significantly lower PD and BOP than did Group B. Furthermore, at 12 weeks, Group A showed greater crestal bone preservation than did Group B. The results of the statistical analysis showed that the two groups were significantly different. Conclusion: The results of this study indicate that simvastatin use as an adjuvant medication after immediate implant insertion contributes to better clinical outcomes and greater crestal bone preservation. Simvastatin may be helpful in increasing bone regeneration, decreasing inflammation, and soft tissue healing. These findings demonstrate how simvastatin may be used as an additional therapy to enhance the effectiveness of rapid implant implantation operations.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=279;epage=282;aulast=Bethaadjuvant therapyclinico-radiographic studycrestal bone levelsimmediate implantssimvastatin |
| spellingShingle | Hymasre Betha M Rajmohan Radhika Thakkar Bezgam R Surya Manoj Shetty Puja Sankla Rahul Tiwari Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic study Journal of Pharmacy and Bioallied Sciences adjuvant therapy clinico-radiographic study crestal bone levels immediate implants simvastatin |
| title | Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic study |
| title_full | Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic study |
| title_fullStr | Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic study |
| title_full_unstemmed | Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic study |
| title_short | Evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants – A clinico radiographic study |
| title_sort | evaluation of crestal bone levels using simvastatin as an adjuvant around immediate implants a clinico radiographic study |
| topic | adjuvant therapy clinico-radiographic study crestal bone levels immediate implants simvastatin |
| url | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=279;epage=282;aulast=Betha |
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