Quinoline- and Isoindoline-Integrated Polycyclic Compounds as Antioxidant, and Antidiabetic Agents Targeting the Dual Inhibition of α-Glycosidase and α-Amylase Enzymes

Quinoline- and Isoindoline-Integrated Polycyclic Compounds as Antioxidant, and Antidiabetic Agents Targeting the Dual Inhibition of α-Glycosidase and α-Amylase Enzymes

Novel analogs of quinoline and isoindoline containing various heterocycles, such as tetrazole, triazole, pyrazole, and pyridine, were synthesized and characterized using FT-IR, NMR, and mass spectroscopy, and their antioxidant and antidiabetic activities were investigated. The previously synthesized...

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Bibliographic Details
Main Authors:	Mohammed Al-Ghorbani, Osama Alharbi, Abdel-Basit Al-Odayni, Naaser A. Y. Abduh
Format:	Article
Language:	English
Published:	MDPI AG 2023-08-01
Series:	Pharmaceuticals
Subjects:	quinoline isoindoline antioxidant antidiabetic molecular docking simulation molecular dynamics simulation
Online Access:	https://www.mdpi.com/1424-8247/16/9/1222

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