Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in China
Colorectal cancer (CRC) screening has been widely implemented in Europe and the USA. However, there is little evidence of participation and diagnostic yields in population-based CRC screening in China. The participation rate and detection of colorectal lesions in this program were reported and relat...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-07-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2020.01173/full |
| _version_ | 1818126891143397376 |
|---|---|
| author | Jiangong Zhang Huifang Xu Liyang Zheng Juan Yu Qiong Chen Xiaoqin Cao Shuzheng Liu Maria Jose Gonzalez Lanwei Guo Lanwei Guo Xibin Sun Shaokai Zhang Youlin Qiao Youlin Qiao |
| author_facet | Jiangong Zhang Huifang Xu Liyang Zheng Juan Yu Qiong Chen Xiaoqin Cao Shuzheng Liu Maria Jose Gonzalez Lanwei Guo Lanwei Guo Xibin Sun Shaokai Zhang Youlin Qiao Youlin Qiao |
| author_sort | Jiangong Zhang |
| collection | DOAJ |
| description | Colorectal cancer (CRC) screening has been widely implemented in Europe and the USA. However, there is little evidence of participation and diagnostic yields in population-based CRC screening in China. The participation rate and detection of colorectal lesions in this program were reported and related factors were explored. The analysis was conducted in the context of the Cancer Screening Program in Urban China, which recruited 282,377 eligible participants aged 40–74 years from eight cities in Henan province from 2013 to 2019. A total of 39,834 participants were evaluated to be high risk for CRC by an established risk score system and were subsequently recommended for colonoscopy. Of 39,834 with high risk for CRC, 7,454 subjects undertook colonoscopy (participation rate of 18.71%). We found that 50–64 years, high level of education, marriage, former smoking, current alcohol drinking, low levels dietary intake of vegetables, high levels dietary intake of processed meat, lack of physical activity, fecal occult blood test positive result, history of colonic polyp, history of colorectitis, and family history of CRC were associated with increased participation of colonoscopy screening. Overall, 17 CRC (0.23%), 95 advanced adenoma (1.27%), 478 non-advanced adenomas dysplasia (6.41%), 248 hyperplastic polyp (3.33%), and 910 other benign lesions (12.21%) were detected. The findings from the study will provide important references for designing effective population-based CRC screening strategies in the future. Given the relatively low participation rate, there was room for improvement in the yield of CRC screening. |
| first_indexed | 2024-12-11T07:08:40Z |
| format | Article |
| id | doaj.art-2810eaffcd5e4d08a3e0fcc11a4a9986 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-11T07:08:40Z |
| publishDate | 2020-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-2810eaffcd5e4d08a3e0fcc11a4a99862022-12-22T01:16:25ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2020-07-011010.3389/fonc.2020.01173549391Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in ChinaJiangong Zhang0Huifang Xu1Liyang Zheng2Juan Yu3Qiong Chen4Xiaoqin Cao5Shuzheng Liu6Maria Jose Gonzalez7Lanwei Guo8Lanwei Guo9Xibin Sun10Shaokai Zhang11Youlin Qiao12Youlin Qiao13Department of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaEndoscopic Diagnosis and Treatment Center, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaSchool of Public Health, Dalian Medical University, Dalian, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaOffice of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaDepartment of Cancer Epidemiology and Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, ChinaOffice of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaColorectal cancer (CRC) screening has been widely implemented in Europe and the USA. However, there is little evidence of participation and diagnostic yields in population-based CRC screening in China. The participation rate and detection of colorectal lesions in this program were reported and related factors were explored. The analysis was conducted in the context of the Cancer Screening Program in Urban China, which recruited 282,377 eligible participants aged 40–74 years from eight cities in Henan province from 2013 to 2019. A total of 39,834 participants were evaluated to be high risk for CRC by an established risk score system and were subsequently recommended for colonoscopy. Of 39,834 with high risk for CRC, 7,454 subjects undertook colonoscopy (participation rate of 18.71%). We found that 50–64 years, high level of education, marriage, former smoking, current alcohol drinking, low levels dietary intake of vegetables, high levels dietary intake of processed meat, lack of physical activity, fecal occult blood test positive result, history of colonic polyp, history of colorectitis, and family history of CRC were associated with increased participation of colonoscopy screening. Overall, 17 CRC (0.23%), 95 advanced adenoma (1.27%), 478 non-advanced adenomas dysplasia (6.41%), 248 hyperplastic polyp (3.33%), and 910 other benign lesions (12.21%) were detected. The findings from the study will provide important references for designing effective population-based CRC screening strategies in the future. Given the relatively low participation rate, there was room for improvement in the yield of CRC screening.https://www.frontiersin.org/article/10.3389/fonc.2020.01173/fulladherencecolorectal cancerlesionearly detectioncolonoscopy |
| spellingShingle | Jiangong Zhang Huifang Xu Liyang Zheng Juan Yu Qiong Chen Xiaoqin Cao Shuzheng Liu Maria Jose Gonzalez Lanwei Guo Lanwei Guo Xibin Sun Shaokai Zhang Youlin Qiao Youlin Qiao Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in China Frontiers in Oncology adherence colorectal cancer lesion early detection colonoscopy |
| title | Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in China |
| title_full | Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in China |
| title_fullStr | Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in China |
| title_full_unstemmed | Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in China |
| title_short | Determinants of Participation and Detection Rate of Colorectal Cancer From a Population-Based Screening Program in China |
| title_sort | determinants of participation and detection rate of colorectal cancer from a population based screening program in china |
| topic | adherence colorectal cancer lesion early detection colonoscopy |
| url | https://www.frontiersin.org/article/10.3389/fonc.2020.01173/full |
| work_keys_str_mv | AT jiangongzhang determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT huifangxu determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT liyangzheng determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT juanyu determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT qiongchen determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT xiaoqincao determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT shuzhengliu determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT mariajosegonzalez determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT lanweiguo determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT lanweiguo determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT xibinsun determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT shaokaizhang determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT youlinqiao determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina AT youlinqiao determinantsofparticipationanddetectionrateofcolorectalcancerfromapopulationbasedscreeningprograminchina |