M2 macrophage-secreted exosomes promote metastasis and increase vascular permeability in hepatocellular carcinoma

M2 macrophage-secreted exosomes promote metastasis and increase vascular permeability in hepatocellular carcinoma

Abstract Background Metastasis is a key feature of malignant tumors and significantly contributes to their high mortality, particularly in hepatocellular carcinoma (HCC). Therefore, it is imperative to explore the mechanism of tumor metastasis. Recently, tumor-associated macrophages (TAMs) have been...

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Bibliographic Details
Main Authors: Yiwei Lu, Guoyong Han, Yao Zhang, Long Zhang, Zhi Li, Qingyuan Wang, Zhiqiang Chen, Xuehao Wang, Jindao Wu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
M2 macrophages
Exosomes
EMT
Angiogenesis
Vascular permeability
miR-23a-3p
Online Access:https://doi.org/10.1186/s12964-022-00872-w

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