A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV
Background Chronic sleep disruption can have significant negative health effects and prior studies suggest that people with HIV (PWH) have disproportionately higher rates of sleep problems. Methods We evaluated baseline sleep of sedentary, older adults (50–75 years) with (n = 28) and without HIV (n ...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-10-01
|
| Series: | HIV Research & Clinical Practice |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/25787489.2020.1839708 |
| _version_ | 1797661040395157504 |
|---|---|
| author | Brian Hixon Helen J. Burgess Melissa P. Wilson Samantha MaWhinney Catherine M. Jankowski Kristine M. Erlandson |
| author_facet | Brian Hixon Helen J. Burgess Melissa P. Wilson Samantha MaWhinney Catherine M. Jankowski Kristine M. Erlandson |
| author_sort | Brian Hixon |
| collection | DOAJ |
| description | Background Chronic sleep disruption can have significant negative health effects and prior studies suggest that people with HIV (PWH) have disproportionately higher rates of sleep problems. Methods We evaluated baseline sleep of sedentary, older adults (50–75 years) with (n = 28) and without HIV (n = 29) recruited into a 24-week exercise study. Subjective sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI); objective sleep parameters were assessed using wrist-worn actigraphy. Regression models were used to investigate changes in outcomes. Results Fifty-seven participants completed the intervention. At baseline, PWH had significantly lower sleep efficiency (88.7 [95% CI 86, 91]%) compared to controls (91.8 [95% CI 91, 93]%; p = 0.02); other sleep measures indicated poorer sleep among PWH but did not reach statistical significance (p ≥ 0.12). Overall, sleep outcomes did not significantly change with the exercise intervention (all p > 0.05). In adjusted analyses, PWH demonstrated a decrease in total sleep time (–22.1 [–43.7, –0.05] p = 0.045) and sleep efficiency (–1.3 [–2.5, –.01], p = 0.03) during the 24 weeks of exercise; these differences were attenuated and no longer significant after adjusting for exercise intensity. At the completion of the intervention, compared to controls, PWH had significantly poorer sleep by PSQI score (2.2 [0.6, 3.8]; p = 0.006) and sleep efficiency (–2.8 [–5.4,–0.2]%; p = 0.04). Conclusions In this study, sleep disturbance was more prevalent in sedentary older PWH compared to uninfected controls. An exercise intervention had minimal effect on sleep impairments among PWH nor controls. Among older adults, interventions beyond cardiovascular and resistance exercise may be needed to significantly alter subjective and objective sleep outcomes. |
| first_indexed | 2024-03-11T18:39:36Z |
| format | Article |
| id | doaj.art-2813f98e2f90480c9939b32a32e29647 |
| institution | Directory Open Access Journal |
| issn | 2578-7470 |
| language | English |
| last_indexed | 2024-03-11T18:39:36Z |
| publishDate | 2020-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | HIV Research & Clinical Practice |
| spelling | doaj.art-2813f98e2f90480c9939b32a32e296472023-10-12T13:43:52ZengTaylor & Francis GroupHIV Research & Clinical Practice2578-74702020-10-0121512112910.1080/25787489.2020.18397081839708A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIVBrian Hixon0Helen J. Burgess1Melissa P. Wilson2Samantha MaWhinney3Catherine M. Jankowski4Kristine M. Erlandson5University of Colorado, Colorado School of Public Health, Aurora, CO, USADepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USADepartment of Biostatistics and Informatics, University of Colorado, Aurora, CO, USADepartment of Biostatistics and Informatics, University of Colorado, Aurora, CO, USACollege of Nursing, University of Colorado, Aurora, CO, USADepartment of Medicine, University of Colorado, Aurora, CO, USABackground Chronic sleep disruption can have significant negative health effects and prior studies suggest that people with HIV (PWH) have disproportionately higher rates of sleep problems. Methods We evaluated baseline sleep of sedentary, older adults (50–75 years) with (n = 28) and without HIV (n = 29) recruited into a 24-week exercise study. Subjective sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI); objective sleep parameters were assessed using wrist-worn actigraphy. Regression models were used to investigate changes in outcomes. Results Fifty-seven participants completed the intervention. At baseline, PWH had significantly lower sleep efficiency (88.7 [95% CI 86, 91]%) compared to controls (91.8 [95% CI 91, 93]%; p = 0.02); other sleep measures indicated poorer sleep among PWH but did not reach statistical significance (p ≥ 0.12). Overall, sleep outcomes did not significantly change with the exercise intervention (all p > 0.05). In adjusted analyses, PWH demonstrated a decrease in total sleep time (–22.1 [–43.7, –0.05] p = 0.045) and sleep efficiency (–1.3 [–2.5, –.01], p = 0.03) during the 24 weeks of exercise; these differences were attenuated and no longer significant after adjusting for exercise intensity. At the completion of the intervention, compared to controls, PWH had significantly poorer sleep by PSQI score (2.2 [0.6, 3.8]; p = 0.006) and sleep efficiency (–2.8 [–5.4,–0.2]%; p = 0.04). Conclusions In this study, sleep disturbance was more prevalent in sedentary older PWH compared to uninfected controls. An exercise intervention had minimal effect on sleep impairments among PWH nor controls. Among older adults, interventions beyond cardiovascular and resistance exercise may be needed to significantly alter subjective and objective sleep outcomes.http://dx.doi.org/10.1080/25787489.2020.1839708sleephivexercisephysical activityfrail |
| spellingShingle | Brian Hixon Helen J. Burgess Melissa P. Wilson Samantha MaWhinney Catherine M. Jankowski Kristine M. Erlandson A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV HIV Research & Clinical Practice sleep hiv exercise physical activity frail |
| title | A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV |
| title_full | A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV |
| title_fullStr | A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV |
| title_full_unstemmed | A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV |
| title_short | A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV |
| title_sort | supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without hiv |
| topic | sleep hiv exercise physical activity frail |
| url | http://dx.doi.org/10.1080/25787489.2020.1839708 |
| work_keys_str_mv | AT brianhixon asupervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT helenjburgess asupervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT melissapwilson asupervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT samanthamawhinney asupervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT catherinemjankowski asupervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT kristinemerlandson asupervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT brianhixon supervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT helenjburgess supervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT melissapwilson supervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT samanthamawhinney supervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT catherinemjankowski supervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv AT kristinemerlandson supervisedexerciseinterventionfailstoimprovesubjectiveandobjectivesleepmeasuresamongolderadultswithandwithouthiv |