Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging Platform

This article presents and validates a newly developed GATE model of the Siemens Inveon trimodal imaging platform. Fully incorporating the positron emission tomography (PET), single-photon emission computed tomography (SPECT), and computed tomography (CT) data acquisition subsystems, this model enabl...

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Main Authors: Sanghyeb Lee, Jens Gregor, Dustin Osborne
Format: Article
Language:English
Published: SAGE Publications 2013-10-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2013.00058
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author Sanghyeb Lee
Jens Gregor
Dustin Osborne
author_facet Sanghyeb Lee
Jens Gregor
Dustin Osborne
author_sort Sanghyeb Lee
collection DOAJ
description This article presents and validates a newly developed GATE model of the Siemens Inveon trimodal imaging platform. Fully incorporating the positron emission tomography (PET), single-photon emission computed tomography (SPECT), and computed tomography (CT) data acquisition subsystems, this model enables feasibility studies of new imaging applications, the development of reconstruction and correction algorithms, and the creation of a baseline against which experimental results for real data can be compared. Model validation was based on comparing simulation results against both empirical and published data. The PET modality was validated using the NEMA NU-4 standard. Validations of SPECT and CT modalities were based on assessment of model accuracy compared to published and empirical data on the platform. Validation results show good agreement between simulation and empirical data of approximately ± 5%.
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spelling doaj.art-28150a5f1c024629a3e8904114ee78882024-03-02T00:31:51ZengSAGE PublicationsMolecular Imaging1536-01212013-10-011210.2310/7290.2013.0005810.2310_7290.2013.00058Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging PlatformSanghyeb LeeJens GregorDustin OsborneThis article presents and validates a newly developed GATE model of the Siemens Inveon trimodal imaging platform. Fully incorporating the positron emission tomography (PET), single-photon emission computed tomography (SPECT), and computed tomography (CT) data acquisition subsystems, this model enables feasibility studies of new imaging applications, the development of reconstruction and correction algorithms, and the creation of a baseline against which experimental results for real data can be compared. Model validation was based on comparing simulation results against both empirical and published data. The PET modality was validated using the NEMA NU-4 standard. Validations of SPECT and CT modalities were based on assessment of model accuracy compared to published and empirical data on the platform. Validation results show good agreement between simulation and empirical data of approximately ± 5%.https://doi.org/10.2310/7290.2013.00058
spellingShingle Sanghyeb Lee
Jens Gregor
Dustin Osborne
Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging Platform
Molecular Imaging
title Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging Platform
title_full Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging Platform
title_fullStr Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging Platform
title_full_unstemmed Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging Platform
title_short Development and Validation of a Complete GATE Model of the Siemens Inveon Trimodal Imaging Platform
title_sort development and validation of a complete gate model of the siemens inveon trimodal imaging platform
url https://doi.org/10.2310/7290.2013.00058
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