Antibodies in action: the role of humoral immunity in the fight against atherosclerosis
Abstract The sequestering of oxidation-modified low-density lipoprotein by macrophages results in the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes a release of intercellular epitopes and the activation of the adaptive immune system, which we predict lea...
Main Authors: | Joshua A. Taylor, Mark A. Hutchinson, Patricia J. Gearhart, Robert W. Maul |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12979-022-00316-6 |
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