Antibodies in action: the role of humoral immunity in the fight against atherosclerosis

Antibodies in action: the role of humoral immunity in the fight against atherosclerosis

Abstract The sequestering of oxidation-modified low-density lipoprotein by macrophages results in the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes a release of intercellular epitopes and the activation of the adaptive immune system, which we predict lea...

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Bibliographic Details
Main Authors: Joshua A. Taylor, Mark A. Hutchinson, Patricia J. Gearhart, Robert W. Maul
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Immunity & Ageing
Subjects:
AID
Atherosclerosis
B cells
Antibodies
Online Access:https://doi.org/10.1186/s12979-022-00316-6

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