CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary

CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary

<b>: </b>Most high‐grade serous ovarian cancers (HGSCs) initiate from the fallopian tube epithelium and then metastasize to the ovary and throughout the abdomen. Genomic analyses suggest that most HGSCs seed the ovary prior to abdominal dissemination. Similarly, animal models support a c...

Full description

Bibliographic Details
Main Authors: Shoumei Bai, Wanhong Zhu, Lan Coffman, Anda Vlad, Lauren E. Schwartz, Esther Elishaev, Ronny Drapkin, Ronald J Buckanovich
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
high-grade serous ovarian cancers
hematogenous spread
endoglin (cd105)
tgf-trc105
serous tubal intraepithelial carcinoma (stic)
Online Access:https://www.mdpi.com/2072-6694/11/11/1710

Internet

https://www.mdpi.com/2072-6694/11/11/1710

Similar Items