Extra-corporeal detoxification in insects
Upon uptake of toxins, insects launch a detoxification program. This program is deployed in multiple organs and cells to raise their tolerance against the toxin. The molecular mechanisms of this program inside the insect body have been studied and understood in detail. Here, we report on a yet unexp...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024044232 |
| _version_ | 1827310634058907648 |
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| author | Jing Yang Yiwen Wang Abeer El Wakil Bernard Moussian |
| author_facet | Jing Yang Yiwen Wang Abeer El Wakil Bernard Moussian |
| author_sort | Jing Yang |
| collection | DOAJ |
| description | Upon uptake of toxins, insects launch a detoxification program. This program is deployed in multiple organs and cells to raise their tolerance against the toxin. The molecular mechanisms of this program inside the insect body have been studied and understood in detail. Here, we report on a yet unexplored extra-corporeal detoxification of insecticides in Drosophila melanogaster. Wild-type D. melanogaster incubated with DDT, a contact insecticide, in a closed environment died as expected. However, incubation of a second cohort in the same environment after removal of the dead flies was not lethal. The effect was significantly lower if the flies of the two cohorts were unrelated. Incubation assays with Chlorpyrifos, another contact insecticide, yielded identical results, while incubation assays with Chlorantraniliprole, again a contact insecticide, was toxic for the second cohort of flies. A cohort of flies incubated in a DDT environment after an initial incubation of a honeybee survived treatment. Together, our data suggest that insects including Apis mellifera and D. melanogaster have the capacity to modify their proximate environment. Consequently, in their ecological niche, following individuals might be saved from intoxication thereby facilitating colonisation of an attractive site. |
| first_indexed | 2024-04-24T20:03:12Z |
| format | Article |
| id | doaj.art-281a536429ec42af91b3de9be4bc7372 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T20:03:12Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-281a536429ec42af91b3de9be4bc73722024-03-24T06:59:44ZengElsevierHeliyon2405-84402024-04-01107e28392Extra-corporeal detoxification in insectsJing Yang0Yiwen Wang1Abeer El Wakil2Bernard Moussian3Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, GermanySchool of Pharmaceutical Science and Technology, University of Tianjin, Tianjin, China; Corresponding author.Department of Biological and Geological Sciences, Faculty of Education, Alexandria University, Alexandria, Egypt; Corresponding author.Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, Germany; Université Côte d'Azur, INRAE, CNRS, Institut Sophia Agrobiotech, Sophia Antipolis, France; Corresponding author. Université Côte d'Azur, INRAE, CNRS, Institut Sophia Agrobiotech, Sophia Atipolis, France.Upon uptake of toxins, insects launch a detoxification program. This program is deployed in multiple organs and cells to raise their tolerance against the toxin. The molecular mechanisms of this program inside the insect body have been studied and understood in detail. Here, we report on a yet unexplored extra-corporeal detoxification of insecticides in Drosophila melanogaster. Wild-type D. melanogaster incubated with DDT, a contact insecticide, in a closed environment died as expected. However, incubation of a second cohort in the same environment after removal of the dead flies was not lethal. The effect was significantly lower if the flies of the two cohorts were unrelated. Incubation assays with Chlorpyrifos, another contact insecticide, yielded identical results, while incubation assays with Chlorantraniliprole, again a contact insecticide, was toxic for the second cohort of flies. A cohort of flies incubated in a DDT environment after an initial incubation of a honeybee survived treatment. Together, our data suggest that insects including Apis mellifera and D. melanogaster have the capacity to modify their proximate environment. Consequently, in their ecological niche, following individuals might be saved from intoxication thereby facilitating colonisation of an attractive site.http://www.sciencedirect.com/science/article/pii/S2405844024044232XenobioticInsecticideDetoxificationDrosophilaKin selection |
| spellingShingle | Jing Yang Yiwen Wang Abeer El Wakil Bernard Moussian Extra-corporeal detoxification in insects Heliyon Xenobiotic Insecticide Detoxification Drosophila Kin selection |
| title | Extra-corporeal detoxification in insects |
| title_full | Extra-corporeal detoxification in insects |
| title_fullStr | Extra-corporeal detoxification in insects |
| title_full_unstemmed | Extra-corporeal detoxification in insects |
| title_short | Extra-corporeal detoxification in insects |
| title_sort | extra corporeal detoxification in insects |
| topic | Xenobiotic Insecticide Detoxification Drosophila Kin selection |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024044232 |
| work_keys_str_mv | AT jingyang extracorporealdetoxificationininsects AT yiwenwang extracorporealdetoxificationininsects AT abeerelwakil extracorporealdetoxificationininsects AT bernardmoussian extracorporealdetoxificationininsects |