Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA
Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback pro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-04-01
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| Series: | Frontiers in Computational Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fncom.2018.00019/full |
| _version_ | 1818862459371388928 |
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| author | Denis A. Adamchik Valery V. Matrosov Victor B. Kazantsev |
| author_facet | Denis A. Adamchik Valery V. Matrosov Victor B. Kazantsev |
| author_sort | Denis A. Adamchik |
| collection | DOAJ |
| description | Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback provided by the GABA mediated transmembrane current enriched the repertoire of population activity by enabling the oscillatory behavior. This behavior appeared in the form of relaxation oscillations which can be considered as a specific type of brainwaves. |
| first_indexed | 2024-12-19T10:00:12Z |
| format | Article |
| id | doaj.art-281cef2a78b14b109e9f091100263601 |
| institution | Directory Open Access Journal |
| issn | 1662-5188 |
| language | English |
| last_indexed | 2024-12-19T10:00:12Z |
| publishDate | 2018-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Computational Neuroscience |
| spelling | doaj.art-281cef2a78b14b109e9f0911002636012022-12-21T20:26:41ZengFrontiers Media S.A.Frontiers in Computational Neuroscience1662-51882018-04-011210.3389/fncom.2018.00019355378Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABADenis A. AdamchikValery V. MatrosovVictor B. KazantsevDynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback provided by the GABA mediated transmembrane current enriched the repertoire of population activity by enabling the oscillatory behavior. This behavior appeared in the form of relaxation oscillations which can be considered as a specific type of brainwaves.http://journal.frontiersin.org/article/10.3389/fncom.2018.00019/fullneural oscillationrate modeltonic conductanceGABAinterneurons |
| spellingShingle | Denis A. Adamchik Valery V. Matrosov Victor B. Kazantsev Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA Frontiers in Computational Neuroscience neural oscillation rate model tonic conductance GABA interneurons |
| title | Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA |
| title_full | Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA |
| title_fullStr | Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA |
| title_full_unstemmed | Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA |
| title_short | Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA |
| title_sort | emergence of relaxation oscillations in neurons interacting with non stationary ambient gaba |
| topic | neural oscillation rate model tonic conductance GABA interneurons |
| url | http://journal.frontiersin.org/article/10.3389/fncom.2018.00019/full |
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