Common proteins analysis of different mammals' mature milk by 4D-Label-Free
The milk proteins from samples of 13 different animals were identified utilizing 4D-Label-Free proteomics technology, leading to the identification of a substantial number of proteins. Among the various samples, Chinese people (CHP) milk proteins exhibited the highest count, with 1149 distinct prote...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-06-01
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| Series: | Food Chemistry: X |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157524001500 |
| _version_ | 1827224471358930944 |
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| author | Rui Chen Yinggang Sun Yanzhi Wu Yanjun Qiao Qiu Zhang Qian Li Xiaowei Wang Yuan Pan Siyi Li Yining Liu Zeying Wang |
| author_facet | Rui Chen Yinggang Sun Yanzhi Wu Yanjun Qiao Qiu Zhang Qian Li Xiaowei Wang Yuan Pan Siyi Li Yining Liu Zeying Wang |
| author_sort | Rui Chen |
| collection | DOAJ |
| description | The milk proteins from samples of 13 different animals were identified utilizing 4D-Label-Free proteomics technology, leading to the identification of a substantial number of proteins. Among the various samples, Chinese people (CHP) milk proteins exhibited the highest count, with 1149 distinct proteins. Simultaneously, we identified common proteins present in these animal milk. It's notable presence in goat milk contributes to enhancing infant infection resistance, showcasing the beneficial role of lactoperoxidase. Galectin-3 binding protein (Gal-3BP) and tetraspanin in human milk are significantly higher than those in other animals, which determine the prominent antiviral effect of human milk and the important processes related to cell transduction. Furthermore, human milk, camel milk, goat milk and sheep milk proved to be rich sources of milk fat globule membrane (MFGM) proteins. The insights obtained from this study can serve as a foundational framework for exploring the role of different animal milk proteins in disease treatment and the composition of infant formula. |
| first_indexed | 2024-03-07T15:46:14Z |
| format | Article |
| id | doaj.art-281e7c7e895a45ca831fb9f0e4d818dd |
| institution | Directory Open Access Journal |
| issn | 2590-1575 |
| language | English |
| last_indexed | 2025-03-21T17:10:48Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj.art-281e7c7e895a45ca831fb9f0e4d818dd2024-06-14T05:44:21ZengElsevierFood Chemistry: X2590-15752024-06-0122101263Common proteins analysis of different mammals' mature milk by 4D-Label-FreeRui Chen0Yinggang Sun1Yanzhi Wu2Yanjun Qiao3Qiu Zhang4Qian Li5Xiaowei Wang6Yuan Pan7Siyi Li8Yining Liu9Zeying Wang10College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaCorresponding author.; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, ChinaThe milk proteins from samples of 13 different animals were identified utilizing 4D-Label-Free proteomics technology, leading to the identification of a substantial number of proteins. Among the various samples, Chinese people (CHP) milk proteins exhibited the highest count, with 1149 distinct proteins. Simultaneously, we identified common proteins present in these animal milk. It's notable presence in goat milk contributes to enhancing infant infection resistance, showcasing the beneficial role of lactoperoxidase. Galectin-3 binding protein (Gal-3BP) and tetraspanin in human milk are significantly higher than those in other animals, which determine the prominent antiviral effect of human milk and the important processes related to cell transduction. Furthermore, human milk, camel milk, goat milk and sheep milk proved to be rich sources of milk fat globule membrane (MFGM) proteins. The insights obtained from this study can serve as a foundational framework for exploring the role of different animal milk proteins in disease treatment and the composition of infant formula.http://www.sciencedirect.com/science/article/pii/S2590157524001500ProteomicsLactadherinLactoperoxidaseInfantGoat |
| spellingShingle | Rui Chen Yinggang Sun Yanzhi Wu Yanjun Qiao Qiu Zhang Qian Li Xiaowei Wang Yuan Pan Siyi Li Yining Liu Zeying Wang Common proteins analysis of different mammals' mature milk by 4D-Label-Free Food Chemistry: X Proteomics Lactadherin Lactoperoxidase Infant Goat |
| title | Common proteins analysis of different mammals' mature milk by 4D-Label-Free |
| title_full | Common proteins analysis of different mammals' mature milk by 4D-Label-Free |
| title_fullStr | Common proteins analysis of different mammals' mature milk by 4D-Label-Free |
| title_full_unstemmed | Common proteins analysis of different mammals' mature milk by 4D-Label-Free |
| title_short | Common proteins analysis of different mammals' mature milk by 4D-Label-Free |
| title_sort | common proteins analysis of different mammals mature milk by 4d label free |
| topic | Proteomics Lactadherin Lactoperoxidase Infant Goat |
| url | http://www.sciencedirect.com/science/article/pii/S2590157524001500 |
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