Ovarian granulosa cells utilize scavenger receptor SR-BI to evade cellular cholesterol homeostatic control for steroid synthesis

Ovarian granulosa cells utilize scavenger receptor SR-BI to evade cellular cholesterol homeostatic control for steroid synthesis

Cellular cholesterol is known to be under homeostatic control in nonsteroidogenic cells, and this intrigued us to understand how such control works in steroidogenic cells that additionally use cholesterol for steroid hormone synthesis. We employed primary culture of rat ovarian granulosa cells to st...

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Bibliographic Details
Main Authors: Wei-An Lai (賴薇安), Yi-Ting Yeh (葉伊婷), Ming-Ting Lee (李明亭), Leang-Shin Wu (吳兩新), Ferng-Chun Ke (柯逢春), Jiuan-Jiuan Hwang (黃娟娟
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Journal of Lipid Research
Subjects:
scavenger receptor class B member I
LDL receptor
sterol regulatory element-binding protein
liver receptor homolog-1
follicle-stimulating hormone
transforming growth factor β1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428020

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http://www.sciencedirect.com/science/article/pii/S0022227520428020

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