A Matter of Life or Death: Productively Infected and Bystander CD4 T Cells in Early HIV Infection

A Matter of Life or Death: Productively Infected and Bystander CD4 T Cells in Early HIV Infection

CD4 T cell death or survival following initial HIV infection is crucial for the development of viral reservoirs and latent infection, making its evaluation critical in devising strategies for HIV cure. Here we infected primary CD4 T cells with a wild-type HIV-1 and investigated the death and surviva...

Full description

Bibliographic Details
Main Authors: Dechao Cao, Sushant Khanal, Ling Wang, Zhengke Li, Juan Zhao, Lam Nhat Nguyen, Lam Ngoc Thao Nguyen, Xindi Dang, Madison Schank, Bal Krishna Chand Thakuri, Jinyu Zhang, Zeyuan Lu, Xiao Y. Wu, Zheng D. Morrison, Mohamed El Gazzar, Shunbin Ning, Jonathan P. Moorman, Zhi Q. Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
AKT
ATM
HIV
telomerase
telomere
T cell death
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.626431/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.626431/full

Similar Items