Nitric oxide destabilizes Pias3 and regulates sumoylation.

Nitric oxide destabilizes Pias3 and regulates sumoylation.

Small ubiquitin-related protein modifiers (SUMO) modification is an important mechanism for posttranslational regulation of protein function. However, it is largely unknown how the sumoylation pathway is regulated. Here, we report that nitric oxide (NO) causes global hyposumoylation in mammalian cel...

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Bibliographic Details
Main Authors: Jing Qu, Guang-Hui Liu, Kaiyuan Wu, Peiwei Han, Peng Wang, Jiangmei Li, Xu Zhang, Chang Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2064872?pdf=render

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