Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with review
Abstract Background Peritonitis is a serious and potentially fatal complication of peritoneal dialysis. We report a case of fatal peritonitis caused by Mycobacterium mageritense that was detected for the first time in peritonitis. Case presentation A male patient in his 60 s undergoing peritoneal di...
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | Renal Replacement Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41100-023-00457-4 |
| _version_ | 1797945724560736256 |
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| author | Nobuhiro Hashimoto Nao Kani Shuzo Makino Tomoya Naka Hiromitsu Miyakawa Kazuhiro Okamoto Ryuta Uwatoko Saki Bessho Rei Iio Yoshiyasu Ueda Terumasa Hayashi |
| author_facet | Nobuhiro Hashimoto Nao Kani Shuzo Makino Tomoya Naka Hiromitsu Miyakawa Kazuhiro Okamoto Ryuta Uwatoko Saki Bessho Rei Iio Yoshiyasu Ueda Terumasa Hayashi |
| author_sort | Nobuhiro Hashimoto |
| collection | DOAJ |
| description | Abstract Background Peritonitis is a serious and potentially fatal complication of peritoneal dialysis. We report a case of fatal peritonitis caused by Mycobacterium mageritense that was detected for the first time in peritonitis. Case presentation A male patient in his 60 s undergoing peritoneal dialysis was admitted for catheter diversion with exit-site renewal. The patient had a refractory exit-site infection. Mycobacterial culture was not performed at the exit site prior to admission. After the surgery, the patient developed a fever, and a cloudy effluent was observed. Various antibiotics, including anti-tuberculosis drugs, were administered; however, his symptoms did not improve. The catheter was removed on the thirty-seventh day of admission. Bacteria positive for Ziehl–Neelsen staining were found in the peritoneal sample collected during the surgery. Since nontuberculous mycobacteria were considered the cause of peritonitis, the patient was administered imipenem/cilastatin, amikacin, and clarithromycin. However, he died of septic shock on the fifty-first day after admission. Mycobacterium mageritense was detected in the ascites culture after death. Conclusion This is, to our knowledge, the first report of peritonitis caused by Mycobacterium mageritense. In patients undergoing peritoneal dialysis, when a refractory exit-site infection is observed, mycobacterial culture is necessary to prevent the development of peritonitis. |
| first_indexed | 2024-04-10T20:59:38Z |
| format | Article |
| id | doaj.art-2829d08ff051425f935f0487558dca08 |
| institution | Directory Open Access Journal |
| issn | 2059-1381 |
| language | English |
| last_indexed | 2024-04-10T20:59:38Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Renal Replacement Therapy |
| spelling | doaj.art-2829d08ff051425f935f0487558dca082023-01-22T12:25:39ZengBMCRenal Replacement Therapy2059-13812023-01-01911510.1186/s41100-023-00457-4Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with reviewNobuhiro Hashimoto0Nao Kani1Shuzo Makino2Tomoya Naka3Hiromitsu Miyakawa4Kazuhiro Okamoto5Ryuta Uwatoko6Saki Bessho7Rei Iio8Yoshiyasu Ueda9Terumasa Hayashi10Department of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterDepartment of Kidney Disease and Hypertension, Osaka General Medical CenterAbstract Background Peritonitis is a serious and potentially fatal complication of peritoneal dialysis. We report a case of fatal peritonitis caused by Mycobacterium mageritense that was detected for the first time in peritonitis. Case presentation A male patient in his 60 s undergoing peritoneal dialysis was admitted for catheter diversion with exit-site renewal. The patient had a refractory exit-site infection. Mycobacterial culture was not performed at the exit site prior to admission. After the surgery, the patient developed a fever, and a cloudy effluent was observed. Various antibiotics, including anti-tuberculosis drugs, were administered; however, his symptoms did not improve. The catheter was removed on the thirty-seventh day of admission. Bacteria positive for Ziehl–Neelsen staining were found in the peritoneal sample collected during the surgery. Since nontuberculous mycobacteria were considered the cause of peritonitis, the patient was administered imipenem/cilastatin, amikacin, and clarithromycin. However, he died of septic shock on the fifty-first day after admission. Mycobacterium mageritense was detected in the ascites culture after death. Conclusion This is, to our knowledge, the first report of peritonitis caused by Mycobacterium mageritense. In patients undergoing peritoneal dialysis, when a refractory exit-site infection is observed, mycobacterial culture is necessary to prevent the development of peritonitis.https://doi.org/10.1186/s41100-023-00457-4Nontuberculous mycobacteria (NTM)Mycobacterium mageritensePeritonitisPeritoneal dialysis |
| spellingShingle | Nobuhiro Hashimoto Nao Kani Shuzo Makino Tomoya Naka Hiromitsu Miyakawa Kazuhiro Okamoto Ryuta Uwatoko Saki Bessho Rei Iio Yoshiyasu Ueda Terumasa Hayashi Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with review Renal Replacement Therapy Nontuberculous mycobacteria (NTM) Mycobacterium mageritense Peritonitis Peritoneal dialysis |
| title | Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with review |
| title_full | Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with review |
| title_fullStr | Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with review |
| title_full_unstemmed | Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with review |
| title_short | Fatal peritoneal dialysis-associated peritonitis caused by Mycobacterium mageritense: a case report with review |
| title_sort | fatal peritoneal dialysis associated peritonitis caused by mycobacterium mageritense a case report with review |
| topic | Nontuberculous mycobacteria (NTM) Mycobacterium mageritense Peritonitis Peritoneal dialysis |
| url | https://doi.org/10.1186/s41100-023-00457-4 |
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