Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008
PurposeThe aim of this study was to explore the connection between hemoglobin levels and diabetic retinopathy (DR).MethodsCross-sectional research used data from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. A multiple logistic regression analysis was performed to investig...
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| Format: | Article |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1195647/full |
| _version_ | 1797756280840912896 |
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| author | Xiao Li Meirong Chen |
| author_facet | Xiao Li Meirong Chen |
| author_sort | Xiao Li |
| collection | DOAJ |
| description | PurposeThe aim of this study was to explore the connection between hemoglobin levels and diabetic retinopathy (DR).MethodsCross-sectional research used data from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. A multiple logistic regression analysis was performed to investigate the association between DR and hemoglobin levels. Additionally, generalized additivity models and smoothed curve fitting were carried out.ResultsAfter adjusting for several covariates, there was a negative association between hemoglobin levels and DR in the study, which included 837 participants. The negative association between hemoglobin levels and DR was present in men and women, the obese (BMI > 30), and 60- to 69-year-olds in subgroup analyses stratified by sex, BMI, and age. The association between hemoglobin levels and DR in the normal weight group (BMI < 25) displayed an inverted U-shaped curve with an inflection point of 13.7 (g/dL).ConclusionIn conclusion, our research reveals that high hemoglobin levels are related to a decreased risk of DR. Ascertaining the hemoglobin levels ought to be regarded as an integral facet of the monitoring regimen for patients with diabetic complications and that the risk of DR is reduced through the detection and management of hemoglobin levels. |
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| format | Article |
| id | doaj.art-2831d21a703c40c281473b6869b9b10f |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-12T17:59:12Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-2831d21a703c40c281473b6869b9b10f2023-08-02T13:12:50ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-08-011410.3389/fendo.2023.11956471195647Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008Xiao Li0Meirong Chen1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, ChinaOphthalmology Department, Shandong Hospital of Traditional Chinese Medicine, Jinan, ChinaPurposeThe aim of this study was to explore the connection between hemoglobin levels and diabetic retinopathy (DR).MethodsCross-sectional research used data from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. A multiple logistic regression analysis was performed to investigate the association between DR and hemoglobin levels. Additionally, generalized additivity models and smoothed curve fitting were carried out.ResultsAfter adjusting for several covariates, there was a negative association between hemoglobin levels and DR in the study, which included 837 participants. The negative association between hemoglobin levels and DR was present in men and women, the obese (BMI > 30), and 60- to 69-year-olds in subgroup analyses stratified by sex, BMI, and age. The association between hemoglobin levels and DR in the normal weight group (BMI < 25) displayed an inverted U-shaped curve with an inflection point of 13.7 (g/dL).ConclusionIn conclusion, our research reveals that high hemoglobin levels are related to a decreased risk of DR. Ascertaining the hemoglobin levels ought to be regarded as an integral facet of the monitoring regimen for patients with diabetic complications and that the risk of DR is reduced through the detection and management of hemoglobin levels.https://www.frontiersin.org/articles/10.3389/fendo.2023.1195647/fulldiabetesdiabetic retinopathyNHANEShemoglobincross-sectional study |
| spellingShingle | Xiao Li Meirong Chen Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008 Frontiers in Endocrinology diabetes diabetic retinopathy NHANES hemoglobin cross-sectional study |
| title | Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008 |
| title_full | Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008 |
| title_fullStr | Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008 |
| title_full_unstemmed | Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008 |
| title_short | Correlation of hemoglobin levels with diabetic retinopathy in US adults aged ≥40 years: the NHANES 2005–2008 |
| title_sort | correlation of hemoglobin levels with diabetic retinopathy in us adults aged ≥40 years the nhanes 2005 2008 |
| topic | diabetes diabetic retinopathy NHANES hemoglobin cross-sectional study |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1195647/full |
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