The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome Patients
Objective: To evaluate the effect of continuous positive airway pressure (CPAP) treatment on metabolic syndrome and insuline resistance in patients with obstructive sleep apnea syndrome (OSAS). Materials and Methods: This study evaluated retrospectively with 30 patients who received OSAS diagno...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2017-06-01
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| Series: | Türk Uyku Tıbbı Dergisi |
| Subjects: | |
| Online Access: | http://jtsm.org/archives/archive-detail/article-preview/the-nvestigation-of-the-effect-of-continuous-posit/16539 |
| _version_ | 1797912832028704768 |
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| author | Vasfiye İlbay Mesrure Köseoğlu Bitnel Oya Öztürk Nermin Görkem Şirin İnan Yeşim Kaykı Mehmet İlbay Hayrunisa Dilek Ataklı Aysun Soysal |
| author_facet | Vasfiye İlbay Mesrure Köseoğlu Bitnel Oya Öztürk Nermin Görkem Şirin İnan Yeşim Kaykı Mehmet İlbay Hayrunisa Dilek Ataklı Aysun Soysal |
| author_sort | Vasfiye İlbay |
| collection | DOAJ |
| description | Objective:
To evaluate the effect of continuous positive airway pressure (CPAP) treatment on metabolic syndrome and insuline resistance in patients with obstructive sleep apnea syndrome (OSAS).
Materials and Methods:
This study evaluated retrospectively with 30 patients who received OSAS diagnosis following polysomnography between the years January 2016 - January 2017, whose Respiratory Disturbance Index were above 15, and who were between the ages of 18-78, having no diabetes, chronic liver and kidney disease, malignancy and mental retardation. The anthropometric measures and blood values of these patients before the CPAP treatment and 3 months afterwards were evaluated in their controls. The effect of CPAP treatment on metabolic syndrome and insulin resistance assessed by homeostatic model assessment index was investigated.
Results:
It has been observed that the body mass index (BMI) decreases significantly following the CPAP treatment. No significant changes were found in the anthropometric measurements including the neck circumference, waist circumference, hip circumference, and waist/hip ratios as well as insulin resistance and metabolic syndrome parameters (before of treatment BMI: 31.33±5.58, post treatment BMI: 30.83±7.13, p=0.03). The ESS evaluating the subjective daytime sleepiness following the CPAP treatment has decreased significantly.
Conclusion:
Although this study didn’t improve insulin resistance with assessed homeostatic model assessment, and metabolic syndrome, a significant improvement in BMI and ESS was demonstrated in post treatment. Long-term studies with more cases and with high compliance are needed to demonstrate the effects of CPAP treatment on metabolic syndrome in OSAS patients. |
| first_indexed | 2024-04-10T12:02:09Z |
| format | Article |
| id | doaj.art-2838e94c750648b68f0d49089e0dabef |
| institution | Directory Open Access Journal |
| issn | 2148-1504 |
| language | English |
| last_indexed | 2024-04-10T12:02:09Z |
| publishDate | 2017-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Uyku Tıbbı Dergisi |
| spelling | doaj.art-2838e94c750648b68f0d49089e0dabef2023-02-15T16:16:27ZengGalenos YayineviTürk Uyku Tıbbı Dergisi2148-15042017-06-0142545810.4274/jtsm.09797The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome PatientsVasfiye İlbay0Mesrure Köseoğlu Bitnel1Oya Öztürk2Nermin Görkem Şirin İnan3Yeşim Kaykı4Mehmet İlbay5Hayrunisa Dilek Ataklı6Aysun Soysal7Bakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, TürkiyeBakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, TürkiyeBakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, TürkiyeBakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, TürkiyeBakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, TürkiyeBolu İzzet Baysal Devlet Hastanesi, Acil Servis Kliniği, Bolu, TürkiyeBakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, TürkiyeBakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, TürkiyeObjective: To evaluate the effect of continuous positive airway pressure (CPAP) treatment on metabolic syndrome and insuline resistance in patients with obstructive sleep apnea syndrome (OSAS). Materials and Methods: This study evaluated retrospectively with 30 patients who received OSAS diagnosis following polysomnography between the years January 2016 - January 2017, whose Respiratory Disturbance Index were above 15, and who were between the ages of 18-78, having no diabetes, chronic liver and kidney disease, malignancy and mental retardation. The anthropometric measures and blood values of these patients before the CPAP treatment and 3 months afterwards were evaluated in their controls. The effect of CPAP treatment on metabolic syndrome and insulin resistance assessed by homeostatic model assessment index was investigated. Results: It has been observed that the body mass index (BMI) decreases significantly following the CPAP treatment. No significant changes were found in the anthropometric measurements including the neck circumference, waist circumference, hip circumference, and waist/hip ratios as well as insulin resistance and metabolic syndrome parameters (before of treatment BMI: 31.33±5.58, post treatment BMI: 30.83±7.13, p=0.03). The ESS evaluating the subjective daytime sleepiness following the CPAP treatment has decreased significantly. Conclusion: Although this study didn’t improve insulin resistance with assessed homeostatic model assessment, and metabolic syndrome, a significant improvement in BMI and ESS was demonstrated in post treatment. Long-term studies with more cases and with high compliance are needed to demonstrate the effects of CPAP treatment on metabolic syndrome in OSAS patients.http://jtsm.org/archives/archive-detail/article-preview/the-nvestigation-of-the-effect-of-continuous-posit/16539Obstructive sleep apnea syndromeinsulin resistancecontinuous positive airway pressuremetabolic syndrome |
| spellingShingle | Vasfiye İlbay Mesrure Köseoğlu Bitnel Oya Öztürk Nermin Görkem Şirin İnan Yeşim Kaykı Mehmet İlbay Hayrunisa Dilek Ataklı Aysun Soysal The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome Patients Türk Uyku Tıbbı Dergisi Obstructive sleep apnea syndrome insulin resistance continuous positive airway pressure metabolic syndrome |
| title | The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome Patients |
| title_full | The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome Patients |
| title_fullStr | The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome Patients |
| title_full_unstemmed | The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome Patients |
| title_short | The Investigation of the Effect of Continuous Positive Airway Pressure Treatment on Metabolic Syndrome and Insuline Resistance in Obstructive Sleep Apnea Syndrome Patients |
| title_sort | investigation of the effect of continuous positive airway pressure treatment on metabolic syndrome and insuline resistance in obstructive sleep apnea syndrome patients |
| topic | Obstructive sleep apnea syndrome insulin resistance continuous positive airway pressure metabolic syndrome |
| url | http://jtsm.org/archives/archive-detail/article-preview/the-nvestigation-of-the-effect-of-continuous-posit/16539 |
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