A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line.
Histone modifications regulate gene expression and chromosomal events, yet how histone-modifying enzymes are targeted is poorly understood. Here we report that a conserved DNA repair protein, SMRC-1, associates with MET-2, the C. elegans histone methyltransferase responsible for H3K9me1 and me2 depo...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC6402707?pdf=render |