Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma
Glaucoma diagnosis in highly myopic subjects by optic nerve head (ONH) imaging is challenging as it is difficult to distinguish structural defects related to glaucoma from myopia-related defects in these subjects. Optical coherence tomography (OCT) has evolved to become a routine examination at pres...
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| Format: | Article |
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MDPI AG
2023-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/7/2592 |
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| author | Bachar Kudsieh José Ignacio Fernández-Vigo Ignacio Flores-Moreno Jorge Ruiz-Medrano Maria Garcia-Zamora Muhsen Samaan Jose Maria Ruiz-Moreno |
| author_facet | Bachar Kudsieh José Ignacio Fernández-Vigo Ignacio Flores-Moreno Jorge Ruiz-Medrano Maria Garcia-Zamora Muhsen Samaan Jose Maria Ruiz-Moreno |
| author_sort | Bachar Kudsieh |
| collection | DOAJ |
| description | Glaucoma diagnosis in highly myopic subjects by optic nerve head (ONH) imaging is challenging as it is difficult to distinguish structural defects related to glaucoma from myopia-related defects in these subjects. Optical coherence tomography (OCT) has evolved to become a routine examination at present, providing key information in the assessment of glaucoma based on the study of the ONH. However, the correct segmentation and interpretation of the ONH data employing OCT is still a challenge in highly myopic patients. High-resolution OCT images can help qualitatively and quantitatively describe the structural characteristics and anatomical changes in highly myopic subjects with and without glaucoma. The ONH and peripapillary area can be analyzed to measure the myopic atrophic-related zone, the existence of intrachoroidal cavitation, staphyloma, and ONH pits by OCT. Similarly, the lamina cribosa observed in the OCT images may reveal anatomical changes that justify visual defects. Several quantitative parameters of the ONH obtained from OCT images were proposed to predict the progression of visual defects in glaucoma subjects. Additionally, OCT images help identify factors that may negatively influence the measurement of the retinal nerve fiber layer (RNFL) and provide better analysis using new parameters, such as Bruch’s Membrane Opening-Minimum Rim Width, which serves as an alternative to RNFL measurements in highly myopic subjects due to its superior diagnostic ability. |
| first_indexed | 2024-03-11T05:32:33Z |
| format | Article |
| id | doaj.art-283ac8efd8d64abe8dbad9c9c2b5e095 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T05:32:33Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-283ac8efd8d64abe8dbad9c9c2b5e0952023-11-17T16:59:14ZengMDPI AGJournal of Clinical Medicine2077-03832023-03-01127259210.3390/jcm12072592Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without GlaucomaBachar Kudsieh0José Ignacio Fernández-Vigo1Ignacio Flores-Moreno2Jorge Ruiz-Medrano3Maria Garcia-Zamora4Muhsen Samaan5Jose Maria Ruiz-Moreno6Department of Ophthalmology, University Hospital Puerta De Hierro Majadahonda, 28220 Madrid, SpainCentro Internacional de Oftalmologia Avanzada, 28010 Madrid, SpainDepartment of Ophthalmology, University Hospital Puerta De Hierro Majadahonda, 28220 Madrid, SpainDepartment of Ophthalmology, University Hospital Puerta De Hierro Majadahonda, 28220 Madrid, SpainDepartment of Ophthalmology, University Hospital Puerta De Hierro Majadahonda, 28220 Madrid, SpainBarraquer Eye Clinic UAE, Dubai P.O. Box 212619, United Arab EmiratesDepartment of Ophthalmology, University Hospital Puerta De Hierro Majadahonda, 28220 Madrid, SpainGlaucoma diagnosis in highly myopic subjects by optic nerve head (ONH) imaging is challenging as it is difficult to distinguish structural defects related to glaucoma from myopia-related defects in these subjects. Optical coherence tomography (OCT) has evolved to become a routine examination at present, providing key information in the assessment of glaucoma based on the study of the ONH. However, the correct segmentation and interpretation of the ONH data employing OCT is still a challenge in highly myopic patients. High-resolution OCT images can help qualitatively and quantitatively describe the structural characteristics and anatomical changes in highly myopic subjects with and without glaucoma. The ONH and peripapillary area can be analyzed to measure the myopic atrophic-related zone, the existence of intrachoroidal cavitation, staphyloma, and ONH pits by OCT. Similarly, the lamina cribosa observed in the OCT images may reveal anatomical changes that justify visual defects. Several quantitative parameters of the ONH obtained from OCT images were proposed to predict the progression of visual defects in glaucoma subjects. Additionally, OCT images help identify factors that may negatively influence the measurement of the retinal nerve fiber layer (RNFL) and provide better analysis using new parameters, such as Bruch’s Membrane Opening-Minimum Rim Width, which serves as an alternative to RNFL measurements in highly myopic subjects due to its superior diagnostic ability.https://www.mdpi.com/2077-0383/12/7/2592optic nerve headhigh myopiamyopic glaucomaoptical coherence tomographyperipapillary atrophyoptic disc tilt |
| spellingShingle | Bachar Kudsieh José Ignacio Fernández-Vigo Ignacio Flores-Moreno Jorge Ruiz-Medrano Maria Garcia-Zamora Muhsen Samaan Jose Maria Ruiz-Moreno Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma Journal of Clinical Medicine optic nerve head high myopia myopic glaucoma optical coherence tomography peripapillary atrophy optic disc tilt |
| title | Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma |
| title_full | Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma |
| title_fullStr | Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma |
| title_full_unstemmed | Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma |
| title_short | Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma |
| title_sort | update on the utility of optical coherence tomography in the analysis of the optic nerve head in highly myopic eyes with and without glaucoma |
| topic | optic nerve head high myopia myopic glaucoma optical coherence tomography peripapillary atrophy optic disc tilt |
| url | https://www.mdpi.com/2077-0383/12/7/2592 |
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