Chemotherapy-induced neutropenia elicits metastasis formation in mice by promoting proliferation of disseminated tumor cells

Chemotherapy-induced neutropenia elicits metastasis formation in mice by promoting proliferation of disseminated tumor cells

Chemotherapy is the standard of care for most malignancies. Its tumor debulking effect in adjuvant or neoadjuvant settings is unquestionable, although secondary effects have been reported that paradoxically promote metastasis. Chemotherapy affects the hematopoietic precursors leading to myelosuppres...

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Bibliographic Details
Main Authors: Massimo Russo, Nicolò Panini, Paola Fabbrizio, Laura Formenti, Riccardo Becchetti, Cristina Matteo, Marina Meroni, Claudia Nastasi, Andrea Cappelleri, Roberta Frapolli, Giovanni Nardo, Eugenio Scanziani, Andrea Ponzetta, Maria Rosa Bani, Carmen Ghilardi, Raffaella Giavazzi
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Chemotherapy
lung metastasis
metastasis
myelosuppression
neutropenia
neutrophils
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2239035

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